Interactor 1: COMM (Q24139)
Protein commissureless 1 (Protein commissureless)
Gene: COMM

Interactor 2: NEDD4 (Q9VVI3)
E3 ubiquitin-protein ligase Nedd-4 (DNedd4) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)
Gene: NEDD4

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.55 0.667

The method score is based on:

Property Details
Experiments 12165468, 16531238, 17074801, unassigned4
Identification Methods affinity chromatography technology, pull down, two hybrid, fluorescence technology, nuclear magnetic resonance, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002092 - positive regulation of receptor internalization
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0016199 - axon midline choice point recognition
GO:0031623 - receptor internalization
Homologous interactions 0

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Last updated: 15 Jul 2024