HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	19112176
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 589
+	Hs
		1096260 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		909728 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Dm
		1487784 Q9W1I0_DROME (4-323): 9.26e-62: 204: 48.77		Q9VWD9_DROME (30-582): 3.33e-135: 407: 47.39
+	Hs
		1102127 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		726811 TIA1_HUMAN (99-414): 3.86e-38: 143: 13.57		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		1096089 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		UBQLN_HUMAN (33-453): 5.2e-74: 245: 33.48
+	Hs
		550507 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		1096038 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		DDI2_HUMAN (47-318): 2.04e-49: 178: 13.52
+	Hs
		856663 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		BAG6_HUMAN (25-536): 2.15e-33: 138: 14.66
+	Dm
		1464699 Q9W1I0_DROME (4-323): 9.26e-62: 204: 48.77		Q9V3W9_DROME (37-394): 1.43e-40: 154: 13.95
+	Dm
		1343889 Q8SXP8_DROME (4-389): 1.82e-58: 201: 44.70		Q9V3W9_DROME (37-394): 1.43e-40: 154: 13.95
+	Hs
		856682 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		BAG6_HUMAN (25-536): 2.15e-33: 138: 14.66