HitPredict

Interactor 1: DIAP1 (Q24306)
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
Gene: DIAP1

Interactor 2: Q7JQI1 (Q7JQI1)
Deubiquitinating apoptotic inhibitor, isoform A (EC 3.4.22.-) (Deubiquitinating apoptotic inhibitor, isoform B) (LD36231p)
Gene: DUBAI

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24362437
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 438 Dm			1 852
+	Dm
		1176741 Q9VEM2_DROME (226-296): 2.67e-22: 94.6: 35.53		Q7JQI1_DROME (1-852): 0: 906: 100.00
+	Hs
		177700 BIRC5_HUMAN (36-114): 1.62e-27: 108: 25.88		UBP38_HUMAN (81-826): 0: 581: 24.16
+	Hs
		777082 BIRC6_HUMAN (37-154): 2.35e-34: 138: 32.28		UBP8_HUMAN (269-747): 6.19e-95: 323: 19.92
+	Hs
		271165 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		UBP2_HUMAN (278-746): 2.37e-89: 297: 18.39
+	Hs
		1165224 LRSM1_HUMAN (293-438): 5.05e-24: 106: 20.27		UBP21_HUMAN (286-746): 3.8e-92: 303: 20.12
+	Hs
		271121 LRSM1_HUMAN (293-438): 5.05e-24: 106: 20.27		UBP2_HUMAN (278-746): 2.37e-89: 297: 18.39
+	Hs
		169220 MDM4_HUMAN (257-438): 1.06e-23: 105: 14.65		UBP2_HUMAN (278-746): 2.37e-89: 297: 18.39
+	Hs
		177706 BIRC5_HUMAN (36-114): 1.62e-27: 108: 25.88		USP9X_HUMAN (213-830): 1.15e-80: 287: 16.47
+	Hs
		177733 BIRC5_HUMAN (36-114): 1.62e-27: 108: 25.88		UBP22_HUMAN (319-741): 3.11e-84: 281: 16.40
+	Hs
		169314 MDM4_HUMAN (257-438): 1.06e-23: 105: 14.65		UBP22_HUMAN (319-741): 3.11e-84: 281: 16.40
+	Hs
		1035952 BIRC3_HUMAN (213-401): 2.67e-20: 95.4: 21.08		USP9X_HUMAN (213-830): 1.15e-80: 287: 16.47
+	Hs
		1036311 BIRC2_HUMAN (181-401): 6.9e-20: 94.3: 16.96		USP9X_HUMAN (213-830): 1.15e-80: 287: 16.47
+	Hs
		271156 MYLIP_HUMAN (380-437): 4.78e-16: 81.9: 37.93		UBP2_HUMAN (278-746): 2.37e-89: 297: 18.39
+	Hs
		957751 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UBP7_HUMAN (349-453): 3.31e-20: 98.4: 21.82
+	Hs
		957762 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UBP47_HUMAN (523-806): 1.69e-16: 86.7: 23.78
+	Hs
		169299 MDM4_HUMAN (257-438): 1.06e-23: 105: 14.65		UBP7_HUMAN (349-453): 3.31e-20: 98.4: 21.82
+	Hs
		1035953 BIRC3_HUMAN (213-401): 2.67e-20: 95.4: 21.08		UBP7_HUMAN (349-453): 3.31e-20: 98.4: 21.82
+	Hs
		1036312 BIRC2_HUMAN (181-401): 6.9e-20: 94.3: 16.96		UBP7_HUMAN (349-453): 3.31e-20: 98.4: 21.82
+	Hs
		177729 BIRC5_HUMAN (36-114): 1.62e-27: 108: 25.88		UBP35_HUMAN (400-600): 2.24e-10: 66.5: 16.59
+	Hs
		1036163 BIRC3_HUMAN (213-401): 2.67e-20: 95.4: 21.08		UBP35_HUMAN (400-600): 2.24e-10: 66.5: 16.59