HitPredict

Interactor 1: DIAP1 (Q24306)
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
Gene: DIAP1

Interactor 2: Q7KHK9 (Q7KHK9)
DREAM (LD13366p) (STRICA) (Ser/Thr-rich caspase, isoform A (EC 3.4.22.-)) (Ser/Thr-rich caspase, isoform B)
Gene: Strica

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BIR~Peptidase_C14
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 438 Dm			1 527
+	Dm
		1097090 DIAP2_DROME (41-438): 1.21e-96: 300: 25.00		Q7KHK9_DROME (1-527): 0: 632: 100.00
+	Dm
		136289 DIAP1_DROME (1-438): 9.76e-155: 447: 100.00		DRICE_DROME (236-525): 7.11e-86: 270: 25.95
+	Dm
		137119 DIAP1_DROME (1-438): 9.76e-155: 447: 100.00		CASP1_DROME (285-525): 3.88e-85: 268: 32.21
+	Dm
		1097069 DIAP1_DROME (1-438): 9.76e-155: 447: 100.00		DRONC_DROME (215-523): 7e-74: 243: 17.14
+	Dm
		136290 DIAP2_DROME (41-438): 1.21e-96: 300: 25.00		DRICE_DROME (236-525): 7.11e-86: 270: 25.95
+	Dm
		1097098 DIAP2_DROME (41-438): 1.21e-96: 300: 25.00		CASP8_DROME (274-524): 2.19e-63: 216: 21.86
+	Hs
		957749 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASPA_HUMAN (172-511): 7.84e-105: 325: 21.56
+	Hs
		788182 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP3_HUMAN (263-523): 1.99e-104: 315: 25.89
+	Hs
		788221 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		CASP3_HUMAN (263-523): 1.99e-104: 315: 25.89
+	Mm
		936913 XIAP_MOUSE (2-156): 5.89e-39: 148: 22.01		CASP3_MOUSE (263-523): 5.6e-101: 307: 25.53
+	Hs
		876977 BIRC1_HUMAN (1-222): 1.13e-43: 165: 18.57		CASP9_HUMAN (207-523): 5.51e-92: 288: 21.67
+	Rn
		1337442 XIAP_RAT (2-156): 3.62e-38: 146: 21.38		Q9JHK1_RAT (170-523): 2.72e-97: 304: 21.43
+	Mm
		957027 XIAP_MOUSE (2-156): 5.89e-39: 148: 22.01		CASP7_MOUSE (305-524): 1.06e-94: 292: 26.94
+	Hs
		876939 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP7_HUMAN (273-524): 8.64e-94: 289: 24.56
+	Hs
		876972 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP9_HUMAN (207-523): 5.51e-92: 288: 21.67
+	Hs
		957707 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP8_HUMAN (295-524): 1.03e-89: 285: 24.72
+	Hs
		876960 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		CASP7_HUMAN (273-524): 8.64e-94: 289: 24.56
+	Hs
		877014 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP6_HUMAN (273-523): 2.01e-90: 280: 24.13
+	Hs
		830276 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASP4_HUMAN (259-525): 1.18e-80: 258: 17.91
+	Hs
		957725 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		CASPC_HUMAN (277-525): 3.29e-76: 245: 20.71