HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 164 Hs			1 400
+	Hs
		1028840 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1031475 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		516712 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		993847 SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1084328 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		SIR2_HUMAN (75-380): 1.48e-97: 298: 21.26
+	Mm
		857360 TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70		SIR2_MOUSE (75-380): 2.24e-101: 307: 21.55