HitPredict

Interactor 1: STX5 (Q24509)
Syntaxin-5 (Sed5 protein) (dSed5)
Gene: Syx5

Interactor 2: Q9W3M8 (Q9W3M8)
LD34211p (YKT6 v-SNARE (EC 2.3.1.225))
Gene: Ykt6

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 467 Dm			1 199
+	Dm
		1097995 STX5_DROME (1-451): 0: 517: 100.00		Q7JYX5_DROME (29-198): 1.95e-54: 174: 22.10
+	Dm
		115804 STX5_DROME (1-451): 0: 517: 100.00		M9PGI6_DROME (1-198): 1.95e-54: 174: 17.73
+	Rn
		996535 STX5_RAT (123-450): 1.25e-84: 265: 51.22		YKT6_RAT (2-198): 1.45e-68: 209: 61.93
+	Mm
		1225102 STX5_MOUSE (123-450): 1.28e-82: 260: 51.22		YKT6_MOUSE (2-198): 3.22e-68: 208: 60.91
+	Rn
		996534 STX5_RAT (123-450): 1.25e-84: 265: 51.22		SC22B_RAT (1-198): 1.01e-57: 182: 18.72
+	Hs
		180866 STX5_HUMAN (123-450): 1.28e-73: 237: 50.92		YKT6_HUMAN (2-198): 3.44e-67: 205: 61.42
+	Dm
		1098114 STX1A_DROME (160-467): 3e-64: 211: 14.56		Q9W3M8_DROME (1-199): 1.2e-72: 219: 100.00
+	Hs
		263229 STX5_HUMAN (123-450): 1.28e-73: 237: 50.92		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Mm
		139056 STX1A_MOUSE (161-463): 4.48e-68: 220: 16.50		SC22B_MOUSE (1-198): 1.01e-57: 182: 18.72
+	Hs
		263248 STX1A_HUMAN (161-463): 1.88e-67: 219: 16.17		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Rn
		699183 STX1A_RAT (161-463): 6.87e-68: 220: 16.50		VAMP7_RAT (29-196): 3.55e-56: 178: 19.55
+	Hs
		263179 STX2_HUMAN (161-466): 1.53e-65: 214: 15.36		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Hs
		850569 STX1A_HUMAN (161-463): 1.88e-67: 219: 16.17		VAMP7_HUMAN (29-196): 1.43e-55: 177: 19.55
+	Dm
		1098086 STX1A_DROME (160-467): 3e-64: 211: 14.56		Q7JYX5_DROME (29-198): 1.95e-54: 174: 22.10
+	Dm
		115805 STX1A_DROME (160-467): 3e-64: 211: 14.56		M9PGI6_DROME (1-198): 1.95e-54: 174: 17.73
+	Hs
		263226 STX4_HUMAN (161-466): 5.37e-57: 192: 17.74		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Hs
		850561 STX4_HUMAN (161-466): 5.37e-57: 192: 17.74		VAMP7_HUMAN (29-196): 1.43e-55: 177: 19.55
+	Hs
		1027543 STX5_HUMAN (123-450): 1.28e-73: 237: 50.92		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84
+	Hs
		1083976 STX1A_HUMAN (161-463): 1.88e-67: 219: 16.17		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84
+	Hs
		699279 STX2_HUMAN (161-466): 1.53e-65: 214: 15.36		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84