HitPredict

Interactor 1: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Interactor 2: CAZA1 (P52907)
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Gene: CAPZA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29863498
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 286
+	Hs
		812965 NEK2_HUMAN (1-445): 5.46e-146: 425: 100.00		CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71
+	Hs
		857162 MARK2_HUMAN (2-425): 7.56e-123: 377: 23.56		CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00
+	Hs
		813083 MARK2_HUMAN (2-425): 7.56e-123: 377: 23.56		CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71
+	Hs
		813016 KCC2G_HUMAN (6-433): 8.51e-123: 369: 21.77		CAZA2_HUMAN (1-286): 6.84e-159: 445: 86.71
+	Rn
		70295 AAPK1_RAT (4-383): 1.2e-108: 333: 27.32		CAZA1_RAT (1-286): 4.54e-164: 458: 97.20
+	Rn
		871271 AAPK1_RAT (4-383): 1.2e-108: 333: 27.32		CAZA2_RAT (1-286): 6.2e-159: 445: 86.36
+	Hs
		851397 NEK4_HUMAN (8-271): 2.82e-49: 181: 40.91		CAZA1_HUMAN (1-286): 1.77e-164: 459: 100.00