HitPredict

Interactor 1: STX1A (Q24547)
Syntaxin-1A (dSynt1)
Gene: Syx1A

Interactor 2: Q9W3M8 (Q9W3M8)
LD34211p (YKT6 v-SNARE (EC 2.3.1.225))
Gene: Ykt6

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28403141, 22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin, Synaptobrevin~Syntaxin
Common GO terms	GO:0005484 - SNAP receptor activity GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 291 Dm			1 199
+	Mm
		139056 STX1A_MOUSE (3-290): 3.18e-76: 235: 68.75		SC22B_MOUSE (1-198): 1.01e-57: 182: 18.72
+	Hs
		263248 STX1A_HUMAN (3-290): 2.04e-75: 233: 68.40		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Dm
		1098086 STX1A_DROME (1-291): 4.25e-78: 240: 100.00		Q7JYX5_DROME (29-198): 1.95e-54: 174: 22.10
+	Dm
		115805 STX1A_DROME (1-291): 4.25e-78: 240: 100.00		M9PGI6_DROME (1-198): 1.95e-54: 174: 17.73
+	Rn
		699183 STX1A_RAT (3-290): 2.59e-76: 236: 68.40		VAMP7_RAT (29-196): 3.55e-56: 178: 19.55
+	Hs
		263179 STX2_HUMAN (3-287): 1.3e-73: 229: 60.35		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Hs
		850569 STX1A_HUMAN (3-290): 2.04e-75: 233: 68.40		VAMP7_HUMAN (29-196): 1.43e-55: 177: 19.55
+	At
		812702 SY121_ARATH (29-269): 9.11e-54: 179: 24.10		VA722_ARATH (23-198): 3.72e-73: 222: 19.05
+	At
		1378372 SY121_ARATH (29-269): 9.11e-54: 179: 24.10		VA721_ARATH (23-198): 2.31e-72: 219: 19.58
+	At
		249598 SYP41_ARATH (14-291): 6.18e-53: 177: 16.85		VA721_ARATH (23-198): 2.31e-72: 219: 19.58
+	Hs
		180867 STX3_HUMAN (3-267): 2.31e-57: 187: 58.87		YKT6_HUMAN (2-198): 3.44e-67: 205: 61.42
+	At
		249597 SYP41_ARATH (14-291): 6.18e-53: 177: 16.85		YKT61_ARATH (2-198): 2.62e-67: 206: 42.21
+	Hs
		263226 STX4_HUMAN (3-287): 3.62e-58: 189: 40.41		SC22B_HUMAN (1-198): 1.01e-57: 182: 18.72
+	Hs
		850561 STX4_HUMAN (3-287): 3.62e-58: 189: 40.41		VAMP7_HUMAN (29-196): 1.43e-55: 177: 19.55
+	At
		249586 SYP41_ARATH (14-291): 6.18e-53: 177: 16.85		YKT62_ARATH (2-198): 3.4e-60: 188: 40.30
+	Hs
		850562 STX3_HUMAN (3-267): 2.31e-57: 187: 58.87		VAMP7_HUMAN (29-196): 1.43e-55: 177: 19.55
+	Mm
		936372 Q8BH40_MOUSE (38-289): 5.33e-54: 177: 25.10		VAMP7_MOUSE (29-196): 9.04e-56: 177: 18.99
+	Hs
		1083976 STX1A_HUMAN (3-290): 2.04e-75: 233: 68.40		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84
+	Hs
		699279 STX2_HUMAN (3-287): 1.3e-73: 229: 60.35		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84
+	Hs
		1017753 STX4_HUMAN (3-287): 3.62e-58: 189: 40.41		SC22A_HUMAN (1-147): 1.04e-29: 113: 14.84