Protein: PAAF1
Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71)

Gene: PAAF1
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9BRP4

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000502 - proteasome complex
GO:0005669 - transcription factor TFIID complex
GO:0005829 - cytosol
GO:0006367 - transcription initiation at RNA polymerase II promoter

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

969040

PRS8
26S proteasome regulatory subunit 8

7

17

Small-scale

0.754

High

851409

PRS6B
26S proteasome regulatory subunit 6B

5

16

Small-scale

0.720

High

906592

PSMD7
26S proteasome non-ATPase regulatory subunit 7

5

9

High-throughput

0.720

High

778766

PRS7
26S proteasome regulatory subunit 7

5

14

Small-scale

0.716

High

1411532

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

5

7

High-throughput

0.716

High

610454

PRS6A
26S proteasome regulatory subunit 6A

5

20

Small-scale

0.714

High

968797

PRS4
26S proteasome regulatory subunit 4

5

17

Small-scale

0.714

High

295534

PSD10
26S proteasome non-ATPase regulatory subunit 10

5

12

Small-scale

0.712

High

211030

PSMD3
26S proteasome non-ATPase regulatory subunit 3

4

2

High-throughput

0.697

High

1098114

PSMD2
26S proteasome non-ATPase regulatory subunit 2

4

7

High-throughput

0.694

High

1326257

SESQ1
Sesquipedalian-1

1

20

High-throughput

0.691

High

138293

PSDE
26S proteasome non-ATPase regulatory subunit 14

4

9

Small-scale

0.683

High

128308

PSD12
26S proteasome non-ATPase regulatory subunit 12

3

6

High-throughput

0.671

High

1357860

ZFN2B
AN1-type zinc finger protein 2B

3

1

High-throughput

0.667

High

1411530

PSD13
26S proteasome non-ATPase regulatory subunit 13

2

2

High-throughput

0.628

High

1156482

ADRM1
Proteasomal ubiquitin receptor ADRM1

3

0

High-throughput

0.628

High

128056

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

6

High-throughput

0.621

High

1136582

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

7

High-throughput

0.621

High

1404564

PSMD1
26S proteasome non-ATPase regulatory subunit 1

2

7

High-throughput

0.621

High

930035

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

19

High-throughput

0.618

High

1411527

KPCD2
Serine/threonine-protein kinase D2

1

14

High-throughput

0.618

High

933718

PSMD4
26S proteasome non-ATPase regulatory subunit 4

2

2

High-throughput

0.611

High

874193

PSMD8
26S proteasome non-ATPase regulatory subunit 8

2

1

Small-scale

0.601

High

975494

PRS10
26S proteasome regulatory subunit 10B

2

18

Small-scale

0.601

High

242741

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.584

High

1411529

ZRAN1
Ubiquitin thioesterase ZRANB1

2

10

High-throughput

0.584

High

1358773

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

2

6

Small-scale

0.583

High

954736

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.576

High

1255280

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

128469

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

2

High-throughput

0.536

High

1408131

BAG1
BAG family molecular chaperone regulator 1

1

2

High-throughput

0.536

High

1157417

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

High-throughput

0.513

High

405536

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

1411531

DEOC
Deoxyribose-phosphate aldolase

1

0

High-throughput

0.493

High

607640

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

5

High-throughput

0.479

High

681003

PSA1
Proteasome subunit alpha type-1

1

4

Small-scale

0.479

High

681223

PSA2
Proteasome subunit alpha type-2

1

7

Small-scale

0.479

High

1405756

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

3

High-throughput

0.479

High

1411528

EGLN3
Prolyl hydroxylase EGLN3

1

7

High-throughput

0.479

High

248618

FADS1
Acyl-CoA

1

1

High-throughput

0.470

High

1316093

A16A1
Aldehyde dehydrogenase family 16 member A1

1

5

High-throughput

0.470

High

628013

ANXA7
Annexin A7

1

5

High-throughput

0.464

High

1256923

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.458

High

1136940

ABRX2
BRISC complex subunit Abraxas 2

1

1

Small-scale

0.445

High

418394

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

769023

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

1270328

SPT6H
Transcription elongation factor SPT6

1

6

Small-scale

0.437

High

388795

C1QC
Complement C1q subcomponent subunit C

1

1

High-throughput

0.407

High

1199975

CCD92
Coiled-coil domain-containing protein 92

1

0

High-throughput

0.279

Low

1381897

TET5B
Terminal nucleotidyltransferase 5B

1

0

High-throughput

0.279

Low

1207761

TMM31
Transmembrane protein 31

1

0

High-throughput

0.232

Low

1324270

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025