Protein: RPN14
26S proteasome regulatory subunit RPN14 (Proteasome non-ATPase subunit 14)

Gene: RPN14
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P53196

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918103

PRS8
26S proteasome regulatory subunit 8 homolog

10

14

Small-scale

0.760

High

750979

PRS7
26S proteasome regulatory subunit 7 homolog

10

19

Small-scale

0.756

High

750738

PRS6A
26S proteasome regulatory subunit 6A

7

14

Small-scale

0.747

High

850324

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

2

20

High-throughput

0.737

High

893066

PSD10
Probable 26S proteasome regulatory subunit p28

6

10

Small-scale

0.736

High

750872

PRS6B
26S proteasome regulatory subunit 6B homolog

6

11

Small-scale

0.733

High

803627

RPN1
26S proteasome regulatory subunit RPN1

6

6

Small-scale

0.730

High

850113

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

5

10

Small-scale

0.718

High

918108

RPN8
26S proteasome regulatory subunit RPN8

5

5

Small-scale

0.716

High

798566

HSM3
DNA mismatch repair protein HSM3

6

0

Small-scale

0.698

High

918100

PRS10
26S proteasome subunit RPT4

4

18

Small-scale

0.696

High

918109

RPN5
26S proteasome regulatory subunit RPN5

4

6

Small-scale

0.694

High

826316

PSMD9
Probable 26S proteasome regulatory subunit p27

4

2

Small-scale

0.676

High

817075

RPN3
26S proteasome regulatory subunit RPN3

3

2

High-throughput

0.667

High

822419

PRS4
26S proteasome regulatory subunit 4 homolog

3

12

High-throughput

0.667

High

918106

RPN9
26S proteasome regulatory subunit RPN9

3

2

High-throughput

0.667

High

918107

RPN7
26S proteasome regulatory subunit RPN7

3

5

High-throughput

0.667

High

918110

RPN6
26S proteasome regulatory subunit RPN6

3

4

High-throughput

0.667

High

740194

RPN2
26S proteasome regulatory subunit RPN2

3

5

High-throughput

0.660

High

806776

RPN10
26S proteasome regulatory subunit RPN10

3

2

High-throughput

0.660

High

150299

RPN13
26S proteasome regulatory subunit RPN13

3

0

High-throughput

0.632

High

738330

RPN12
26S proteasome regulatory subunit RPN12

2

1

High-throughput

0.594

High

481698

HSP73
Heat shock protein SSA3

2

16

High-throughput

0.584

High

314896

SEM1
26S proteasome complex subunit SEM1

2

0

High-throughput

0.559

High

918111

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.536

High

359504

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

5

High-throughput

0.500

High

405115

LEU3
3-isopropylmalate dehydrogenase

1

11

High-throughput

0.500

High

408333

GAL1
Galactokinase

1

1

High-throughput

0.500

High

439384

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.500

High

555114

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.500

High

590680

HSP26
Heat shock protein 26

1

4

High-throughput

0.500

High

592385

VATB
V-type proton ATPase subunit B

1

9

High-throughput

0.500

High

645192

PSB4
Proteasome subunit beta type-4

1

3

Small-scale

0.500

High

705779

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

9

High-throughput

0.500

High

918102

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

4

High-throughput

0.500

High

918105

RUVB1
RuvB-like protein 1

1

8

High-throughput

0.500

High

572623

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

813563

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.479

High

707713

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

744004

RAD23
UV excision repair protein RAD23

1

6

High-throughput

0.479

High

803151

ECM29
Proteasome component ECM29

1

12

High-throughput

0.479

High

805830

WSS1
DNA-dependent metalloprotease WSS1

1

1

Small-scale

0.479

High

918101

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

1

High-throughput

0.479

High

661665

MPCP
Mitochondrial phosphate carrier protein

1

11

High-throughput

0.457

High

701550

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

8

High-throughput

0.457

High

823437

MPM1
Mitochondrial peculiar membrane protein 1

1

1

High-throughput

0.457

High

825460

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

11

High-throughput

0.457

High

856549

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

4

High-throughput

0.457

High

510667

HSP77
Import motor subunit, mitochondrial

1

18

High-throughput

0.445

High

545659

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

676192

MAS5
Mitochondrial protein import protein MAS5

1

12

High-throughput

0.445

High

819334

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

918104

ESC1
Silent chromatin protein ESC1

1

5

High-throughput

0.437

High

804819

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025