Interactor 1: U2AF2 (Q24562)
Splicing factor U2AF 50 kDa subunit (U2 auxiliary factor 50 kDa subunit) (U2 snRNP auxiliary factor large subunit)
Gene: U2af50

Interactor 2: U2AF1 (Q94535)
Splicing factor U2af 38 kDa subunit (U2 auxiliary factor 38 kDa subunit) (U2 snRNP auxiliary factor small subunit)
Gene: U2af38

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.942

The method score is based on:

Property Details
Experiments 14605208, 21406555, 9528748, 9632785, 25294943, unassigned4
Identification Methods two hybrid, affinity chromatography technology, experimental interaction detection, anti tag coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~zf-CCCH
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 416
Dm

1 264
+ Dm
+ Hs
+ At
+ Hs
+ Ce
+ Hs
+ At
+ At
+ Hs
+ Sp
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024