HitPredict

Interactor 1: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29531219
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 543
+	Hs
		1334162 POC1A_HUMAN (86-395): 2.66e-76: 243: 16.35		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		881901 ERCC8_HUMAN (1-396): 7.4e-86: 268: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		875939 ERCC8_HUMAN (1-396): 7.4e-86: 268: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		882038 POC1A_HUMAN (86-395): 2.66e-76: 243: 16.35		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		610641 ERCC8_HUMAN (1-396): 7.4e-86: 268: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		965190 WDR5_HUMAN (218-396): 1.27e-45: 161: 20.44		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		876070 POC1A_HUMAN (86-395): 2.66e-76: 243: 16.35		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610775 POC1A_HUMAN (86-395): 2.66e-76: 243: 16.35		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		882075 FBXW7_HUMAN (128-395): 7.43e-59: 204: 13.76		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		610813 FBXW7_HUMAN (128-395): 7.43e-59: 204: 13.76		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		876112 SNR40_HUMAN (140-394): 7.84e-54: 183: 13.79		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		881861 WDR5_HUMAN (218-396): 1.27e-45: 161: 20.44		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882014 WDR5B_HUMAN (220-396): 5.72e-42: 151: 18.99		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		610819 SNR40_HUMAN (140-394): 7.84e-54: 183: 13.79		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		875898 WDR5_HUMAN (218-396): 1.27e-45: 161: 20.44		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610601 WDR5_HUMAN (218-396): 1.27e-45: 161: 20.44		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610750 WDR5B_HUMAN (220-396): 5.72e-42: 151: 18.99		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899369 ERCC8_HUMAN (1-396): 7.4e-86: 268: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899481 POC1A_HUMAN (86-395): 2.66e-76: 243: 16.35		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899326 WDR5_HUMAN (218-396): 1.27e-45: 161: 20.44		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79