HitPredict

Interactor 1: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB

Interactor 2: AKAP9 (Q99996)
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)
Gene: AKAP9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	28514442, 33961781, 32707033, 36736316, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 3907
+	Hs
		568780 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		AKAP9_HUMAN (1-3907): 0: 878: 100.00
+	Hs
		609694 KAPCG_HUMAN (1-351): 5.62e-161: 456: 78.63		AKAP9_HUMAN (1-3907): 0: 878: 100.00
+	Hs
		528359 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH6_HUMAN (571-1660): 2.29e-37: 158: 10.35
+	Hs
		623875 KPCL_HUMAN (6-351): 1.63e-146: 430: 35.75		PLEC_HUMAN (2053-3720): 9.98e-35: 150: 11.45
+	Hs
		610802 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH4_HUMAN (3383-3898): 9.59e-16: 87: 8.43
+	Hs
		568567 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		610795 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH2_HUMAN (3460-3897): 1.17e-12: 77: 7.85
+	Hs
		522538 KAPCB_HUMAN (1-351): 1.47e-164: 464: 100.00		MYH1_HUMAN (3439-3893): 6.81e-12: 74.3: 7.56
+	Hs
		317209 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		PCNT_HUMAN (220-863): 6.95e-11: 71.2: 11.28
+	Hs
		681696 AKT1_HUMAN (2-347): 4.4e-147: 425: 39.03		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Mm
		554901 KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85		MYH6_MOUSE (3369-3901): 5.41e-15: 84.7: 9.57
+	Mm
		554927 KPCE_MOUSE (9-351): 1.24e-139: 415: 35.85		MYH7_MOUSE (3369-3901): 1.05e-14: 84: 8.52
+	Hs
		724784 KPCE_HUMAN (3-351): 3.98e-140: 416: 34.25		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		551616 AKT1_HUMAN (2-347): 4.4e-147: 425: 39.03		DESP_HUMAN (2135-3311): 1.98e-09: 66.5: 13.94
+	Hs
		116964 SGK1_HUMAN (1-348): 5.91e-143: 413: 37.71		MYH1_HUMAN (3439-3893): 6.81e-12: 74.3: 7.56
+	Hs
		551672 KPCE_HUMAN (3-351): 3.98e-140: 416: 34.25		DESP_HUMAN (2135-3311): 1.98e-09: 66.5: 13.94