HitPredict

Interactor 1: Q24590 (Q24590)
Tumor suppressor
Gene: wts

Interactor 2: MOB1 (Q95RA8)
MOB kinase activator-like 1 (Mob as tumor suppressor protein 1) (Dmob1) (Mps one binder kinase activator-like 1)
Gene: mats

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17347649
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1099 Dm			1 219
+	Dm
		1278870 WARTS_DROME (1-1099): 0: 848: 97.56		MOB1_DROME (1-219): 4.13e-114: 326: 100.00
+	Hs
		1185503 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37
+	Hs
		1333705 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51
+	Hs
		1198336 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11
+	Hs
		1285989 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24
+	Hs
		1174306 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41
+	Hs
		325787 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37
+	Hs
		325891 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51
+	Hs
		325791 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11
+	Hs
		325844 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24
+	Hs
		325785 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41
+	Hs
		1185506 ST38L_HUMAN (637-1082): 7.67e-152: 462: 42.95		MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37
+	Hs
		1333714 ST38L_HUMAN (637-1082): 7.67e-152: 462: 42.95		MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51
+	Hs
		325784 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		MOB2_HUMAN (1-213): 5.01e-85: 253: 41.32
+	Hs
		1344983 LATS2_HUMAN (196-1095): 1.21e-165: 519: 41.56		PHOCN_HUMAN (7-201): 2.1e-66: 205: 19.60
+	Sp
		140739 ORB6_SCHPO (630-1081): 3.24e-153: 466: 39.56		MOB2_SCHPO (14-216): 2.75e-85: 254: 38.92
+	Hs
		1174241 ST38L_HUMAN (637-1082): 7.67e-152: 462: 42.95		MOB2_HUMAN (1-213): 5.01e-85: 253: 41.32
+	Sc
		774485 CBK1_YEAST (396-1081): 1.73e-146: 458: 30.92		MOB1_YEAST (2-212): 1.05e-83: 253: 50.47
+	Sc
		797131 CBK1_YEAST (396-1081): 1.73e-146: 458: 30.92		MOB2_YEAST (17-215): 2.15e-81: 246: 36.18
+	Hs
		325949 LATS1_HUMAN (146-1088): 1.64e-156: 496: 41.77		PHOCN_HUMAN (7-201): 2.1e-66: 205: 19.60