HitPredict

Interactor 1: AAK1 (Q2M2I8)
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
Gene: AAK1

Interactor 2: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27173435, 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains OSR1_C~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 961
Hs

1 2382
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024