HitPredict

Interactor 1: SRBS1 (G5EC32)
Sorbin and SH3 domain-containing protein 1 homolog
Gene: sorb-1

Interactor 2: VINC (P19826)
Vinculin (P107B)
Gene: deb-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	0.60	0.494

Property	Details
Experiments	19447967
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0005925 - focal adhesion GO:0097433 - dense body
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1005 Ce			1 1090
+	Hs
		320207 SRBS2_HUMAN (395-1004): 3.88e-47: 185: 20.13		VINC_HUMAN (1-1089): 0: 795: 30.45
+	Hs
		250205 VINEX_HUMAN (323-1004): 1.37e-38: 156: 17.21		VINC_HUMAN (1-1089): 0: 795: 30.45
+	Mm
		1190849 SRBS2_MOUSE (392-1004): 3.77e-39: 160: 18.47		VINC_MOUSE (1-1089): 0: 766: 30.55
+	Hs
		613448 SRBS1_HUMAN (878-1003): 1.57e-20: 100: 32.54		VINC_HUMAN (1-1089): 0: 795: 30.45
+	Hs
		613374 DNMBP_HUMAN (521-742): 6.1e-11: 68.9: 15.19		VINC_HUMAN (1-1089): 0: 795: 30.45
+	Hs
		320216 SRBS2_HUMAN (395-1004): 3.88e-47: 185: 20.13		CTNA1_HUMAN (122-685): 2e-38: 157: 14.85
+	Dm
		53877 A1Z866_DROME (305-1004): 5.92e-50: 189: 17.71		VINC_DROME (1-690): 4.73e-37: 153: 14.92
+	Dm
		234574 Q86P80_DROME (331-1004): 1.15e-48: 186: 17.69		VINC_DROME (1-690): 4.73e-37: 153: 14.92
+	Hs
		764397 DLG5_HUMAN (269-1002): 3.06e-41: 167: 12.27		CTNA1_HUMAN (122-685): 2e-38: 157: 14.85
+	Dm
		2224 A0A0B4K6W0_DROME (62-1004): 1.83e-40: 165: 15.47		VINC_DROME (1-690): 4.73e-37: 153: 14.92
+	Hs
		764423 SRBS1_HUMAN (878-1003): 1.57e-20: 100: 32.54		CTNA1_HUMAN (122-685): 2e-38: 157: 14.85