HitPredict

Interactor 1: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Interactor 2: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	36736316, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 788
+	Hs
		1118439 SNTB1_HUMAN (24-539): 3.07e-150: 443: 55.30		MARK2_HUMAN (1-788): 0: 797: 100.00
+	Hs
		692055 SNTB2_HUMAN (18-540): 9.5e-164: 477: 100.00		MARK3_HUMAN (3-788): 0: 664: 60.15
+	Hs
		1104887 SNTB2_HUMAN (18-540): 9.5e-164: 477: 100.00		MARK1_HUMAN (3-788): 0: 649: 63.35
+	Hs
		692059 SNTB1_HUMAN (24-539): 3.07e-150: 443: 55.30		MARK3_HUMAN (3-788): 0: 664: 60.15
+	Hs
		1118460 SNTB1_HUMAN (24-539): 3.07e-150: 443: 55.30		MARK1_HUMAN (3-788): 0: 649: 63.35
+	Dm
		94938 DLG1_DROME (119-219): 8.57e-15: 79.5: 33.96		E1JGN0_DROME (2-788): 0: 594: 47.79
+	Hs
		1129972 MAGI1_HUMAN (69-261): 1.12e-15: 82.6: 17.96		MELK_HUMAN (44-788): 9.73e-177: 524: 25.17