HitPredict

Interactor 1: GFOD2 (Q3B7J2)
Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-)
Gene: GFOD2

Interactor 2: GFOD1 (Q9NXC2)
Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-)
Gene: GFOD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GFO_IDH_MocA~GFO_IDH_MocA, GFO_IDH_MocA~GFO_IDH_MocA_C
Common GO terms	GO:0000166 - nucleotide binding GO:0005576 - extracellular region GO:0016491 - oxidoreductase activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 385 Hs			1 390
+	Hs
		1347901 GFOD1_HUMAN (3-385): 1.53e-132: 386: 62.44		GFOD1_HUMAN (1-390): 8.78e-156: 445: 100.00
+	Dm
		1376950 Q9Y153_DROME (3-385): 1.92e-114: 340: 43.85		Q9Y153_DROME (1-387): 7.87e-115: 341: 44.08
+	Sp
		144020 YEG9_SCHPO (5-365): 7.29e-89: 274: 19.37		YBQ3_SCHPO (3-352): 5.94e-82: 256: 17.89
+	Sp
		194812 YBQ3_SCHPO (5-353): 7.99e-79: 248: 19.19		YBQ3_SCHPO (3-352): 5.94e-82: 256: 17.89
+	Ec
		761715 NANY_ECOLI (4-385): 2.78e-83: 260: 17.09		NANY_ECOLI (2-261): 7.96e-64: 210: 20.08
+	Sp
		1358096 XDH_SCHPO (4-355): 9.44e-71: 227: 18.23		XDH_SCHPO (2-356): 3.39e-70: 226: 16.40
+	Sc
		381585 GAL80_YEAST (5-367): 1.04e-64: 214: 14.22		GAL80_YEAST (3-366): 7.6e-62: 207: 15.49
+	Ec
		940301 YDGJ_ECOLI (1-349): 4.75e-61: 202: 15.39		YDGJ_ECOLI (3-281): 2.1e-59: 197: 19.15
+	Hs
		858161 BIEA_HUMAN (56-271): 1.09e-42: 152: 15.14		BIEA_HUMAN (54-190): 1.93e-25: 106: 15.83