Interactor 1: HERC2 (O95714)
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)
Gene: HERC2

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.666

The method score is based on:

Property Details
Experiments 25476789, 22261722, 29426014, 35709258
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005814 - centriole
GO:0005829 - cytosol
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 4834
Hs

1 1584
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
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+ Hs
+ Hs
+ Dm

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Last updated: 11Aug2025