HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: NIPS1 (Q9BPW8)
Protein NipSnap homolog 1 (NipSnap1)
Gene: NIPSNAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	30581152, 34037656, 35271311, 39098523, 20562859
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005739 - mitochondrion GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 284
+	Hs
		276123 SQSTM_HUMAN (1-440): 0: 760: 100.00		NIPS2_HUMAN (1-284): 2.88e-152: 428: 68.18
+	Mm
		1225653 SQSTM_MOUSE (1-440): 0: 731: 90.72		Q7TMG8_MOUSE (1-284): 1.14e-150: 424: 68.42
+	Hs
		1128811 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		NIPS1_HUMAN (1-284): 1.14e-161: 452: 100.00
+	Hs
		276128 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		NIPS2_HUMAN (1-284): 2.88e-152: 428: 68.18