HitPredict

Interactor 1: NIPS2 (O75323)
Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence)
Gene: NIPSNAP2

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26043024, 30581152, 34037656, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005739 - mitochondrion GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 440
+	Hs
		1108090 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Mm
		1225653 Q7TMG8_MOUSE (1-286): 1.06e-150: 424: 90.56		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Hs
		276128 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78
+	Hs
		1128811 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78