HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: WDR59 (Q8C0M0)
GATOR2 complex protein WDR59 (CUL4- and DDB1-associated WDR protein 12) (WD repeat-containing protein 59)
Gene: WDR59

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Mm			1 992
+	Hs
		1073029 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		WDR59_HUMAN (1-992): 0: 778: 94.56
+	Hs
		1082202 DDB1_HUMAN (1-1140): 0: 1445: 99.65		RBBP7_HUMAN (43-334): 9.4e-63: 221: 19.80
+	Mm
		291405 DDB1_MOUSE (1-1140): 0: 1446: 100.00		WDR1_MOUSE (15-318): 8.09e-35: 143: 11.03
+	Hs
		1082374 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1R_HUMAN (229-533): 2.38e-33: 137: 10.54
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (320-532): 6.41e-25: 109: 9.87
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (319-532): 1.13e-24: 107: 11.16
+	Hs
		1082355 DDB1_HUMAN (1-1140): 0: 1445: 99.65		GRWD1_HUMAN (96-358): 8.07e-20: 95.7: 15.99
+	Hs
		997738 DDB1_HUMAN (1-1140): 0: 1445: 99.65		RBBP4_HUMAN (124-361): 4.26e-16: 83.7: 16.72
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (359-645): 2.84e-13: 74.5: 9.86
+	At
		186951 DDB1A_ARATH (2-1140): 0: 1254: 52.18		MSI3_ARATH (33-221): 1.18e-21: 101: 15.42
+	At
		186944 DDB1A_ARATH (2-1140): 0: 1254: 52.18		MSI1_ARATH (43-221): 3.86e-20: 96.4: 15.57
+	At
		186950 DDB1B_ARATH (3-1140): 0: 1248: 51.00		MSI3_ARATH (33-221): 1.18e-21: 101: 15.42
+	At
		1340748 DDB1A_ARATH (2-1140): 0: 1254: 52.18		HTD1_ARATH (91-368): 9.38e-18: 89.5: 16.67
+	Hs
		1073168 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		NLE1_HUMAN (174-525): 1.33e-66: 233: 10.89
+	At
		794497 DDB1A_ARATH (2-1140): 0: 1254: 52.18		COP1_ARATH (59-218): 6.62e-11: 68.3: 18.13
+	At
		221820 DDB1B_ARATH (3-1140): 0: 1248: 51.00		COP1_ARATH (59-218): 6.62e-11: 68.3: 18.13
+	Hs
		1073094 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (3-268): 1.34e-53: 201: 18.71
+	Hs
		1073127 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		GRWD1_HUMAN (96-358): 8.07e-20: 95.7: 15.99
+	Ce
		219829 O44985_CAEEL (3-1126): 0: 1022: 19.71		LIN53_CAEEL (92-355): 4.84e-14: 77.6: 16.24
+	Sc
		791185 CFT1_YEAST (11-1125): 0: 673: 14.71		PFS2_YEAST (9-377): 3.7e-57: 206: 18.61