Protein: DKKL1
Dickkopf-like protein 1 (Cancer/testis antigen 34) (CT34) (Protein soggy-1) (SGY-1)

Gene: DKKL1
Organism: Homo sapiens
Interactions: 127
UniProt ID: Q9UK85

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0005615 - extracellular space
GO:0007341 - penetration of zona pellucida
GO:0009653 - anatomical structure morphogenesis
GO:0039706 - co-receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1127612

FAT1
Protocadherin Fat 1

3

8

High-throughput

0.662

High

1294395

FRAS1
Extracellular matrix organizing protein FRAS1

3

11

High-throughput

0.662

High

1039008

NUCB1
Nucleobindin-1

3

0

High-throughput

0.634

High

274931

LRP5
Low-density lipoprotein receptor-related protein 5

2

1

High-throughput

0.628

High

287628

LRP6
Low-density lipoprotein receptor-related protein 6

2

1

High-throughput

0.628

High

611756

BMP7
Bone morphogenetic protein 7

2

2

High-throughput

0.628

High

1211501

FREM2
FRAS1-related extracellular matrix protein 2

2

13

High-throughput

0.628

High

1250369

FAT4
Protocadherin Fat 4

3

9

High-throughput

0.604

High

1439456

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

3

10

High-throughput

0.604

High

1041649

TGBR3
Transforming growth factor beta receptor type 3

2

0

High-throughput

0.602

High

551901

CO6A2

2

0

High-throughput

0.576

High

1251523

CD109
CD109 antigen

2

0

High-throughput

0.576

High

61679

VWA8
von Willebrand factor A domain-containing protein 8

2

1

High-throughput

0.574

High

186351

RA51B
DNA repair protein RAD51 homolog 2

2

3

High-throughput

0.574

High

219099

RA51C
DNA repair protein RAD51 homolog 3

2

3

High-throughput

0.574

High

231780

PEX1
Peroxisomal ATPase PEX1

2

3

High-throughput

0.574

High

239894

PCDH7
Protocadherin-7

2

13

High-throughput

0.574

High

292404

RA51D
DNA repair protein RAD51 homolog 4

2

3

High-throughput

0.574

High

337286

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

2

1

High-throughput

0.574

High

922848

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

2

1

High-throughput

0.574

High

1112274

PEX6
Peroxisomal ATPase PEX6

2

3

High-throughput

0.574

High

1116748

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

2

1

High-throughput

0.574

High

1330145

PCD20
Protocadherin-20

2

10

High-throughput

0.574

High

1333210

AFG2A
ATPase family gene 2 protein homolog A

2

3

High-throughput

0.574

High

1335934

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

2

1

High-throughput

0.574

High

1351812

FAT3
Protocadherin Fat 3

2

12

High-throughput

0.574

High

1411856

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

2

High-throughput

0.574

High

1415611

AFG2B
ATPase family gene 2 protein homolog B

2

3

High-throughput

0.574

High

1449713

MDN1
Midasin

2

1

High-throughput

0.574

High

1452764

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

2

13

High-throughput

0.574

High

1452769

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

2

10

High-throughput

0.574

High

1460963

PCDGB
Protocadherin gamma-A11

2

7

High-throughput

0.574

High

1417280

TMM59
Transmembrane protein 59

2

1

High-throughput

0.549

High

894446

MMP14
Matrix metalloproteinase-14

1

2

High-throughput

0.536

High

903007

MMP15
Matrix metalloproteinase-15

1

2

High-throughput

0.536

High

999703

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.536

High

1291537

FJX1
Four-jointed box protein 1

1

0

High-throughput

0.518

High

133212

QSOX1
Sulfhydryl oxidase 1

1

0

High-throughput

0.513

High

1367864

HTRA1
Serine protease HTRA1

1

0

High-throughput

0.513

High

1459939

PCS1N
ProSAAS

1

0

High-throughput

0.513

High

1460907

NOCT
Nocturnin

1

0

High-throughput

0.513

High

1460957

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.513

High

164748

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

1

High-throughput

0.489

High

220067

XRCC2
DNA repair protein XRCC2

1

3

High-throughput

0.489

High

380781

HBD
Hemoglobin subunit delta

1

1

High-throughput

0.489

High

565732

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.489

High

931311

AT12A
Potassium-transporting ATPase alpha chain 2

1

1

High-throughput

0.489

High

1062196

PCDH1
Protocadherin-1

1

15

High-throughput

0.489

High

1151105

PCH2
Pachytene checkpoint protein 2 homolog

1

1

High-throughput

0.489

High

1207022

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

2

High-throughput

0.489

High

1251226

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

1

High-throughput

0.489

High

1286311

GALT7
N-acetylgalactosaminyltransferase 7

1

1

High-throughput

0.489

High

1307364

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

2

High-throughput

0.489

High

1312546

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

1

High-throughput

0.489

High

1360646

AGRV1
Adhesion G-protein coupled receptor V1

1

6

High-throughput

0.489

High

1460892

TM59L
Transmembrane protein 59-like

1

1

High-throughput

0.489

High

1460952

SARDH
Sarcosine dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

362403

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.479

High

183870

VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1

1

1

High-throughput

0.445

High

440778

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.437

High

300062

CBPD
Carboxypeptidase D

1

0

High-throughput

0.426

High

552484

FA5
Coagulation factor V

1

0

High-throughput

0.426

High

683761

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.426

High

1250385

PCD23
Protocadherin-23

1

8

High-throughput

0.407

High

1288711

CAD24
Cadherin-24

1

1

High-throughput

0.407

High

1395504

PCD16
Protocadherin-16

1

11

High-throughput

0.407

High

1460954

PCDB8
Protocadherin beta-8

1

7

High-throughput

0.407

High

1460955

PCDBA
Protocadherin beta-10

1

7

High-throughput

0.407

High

1460958

PCDB2
Protocadherin beta-2

1

7

High-throughput

0.407

High

1460959

PCDBE
Protocadherin beta-14

1

7

High-throughput

0.407

High

1460960

PCDBD
Protocadherin beta-13

1

7

High-throughput

0.407

High

1460961

PCDBB
Protocadherin beta-11

1

7

High-throughput

0.407

High

1460962

PCDGD
Protocadherin gamma-B1

1

7

High-throughput

0.407

High

62222

DEN11
DENN domain-containing protein 11

3

0

High-throughput

0.345

High

876739

HSP13
Heat shock 70 kDa protein 13

3

0

High-throughput

0.345

High

213002

HS12A
Heat shock 70 kDa protein 12A

2

0

High-throughput

0.328

High

270061

XYLK
Glycosaminoglycan xylosylkinase

2

0

High-throughput

0.328

High

317944

LTN1
E3 ubiquitin-protein ligase listerin

2

0

High-throughput

0.328

High

607723

DCAM
S-adenosylmethionine decarboxylase proenzyme

2

0

High-throughput

0.328

High

618212

AMD
Peptidyl-glycine alpha-amidating monooxygenase

2

0

High-throughput

0.328

High

626036

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

2

0

High-throughput

0.328

High

725677

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

2

0

High-throughput

0.328

High

878288

DPOD2
DNA polymerase delta subunit 2

2

0

High-throughput

0.328

High

882944

EFTU
Elongation factor Tu, mitochondrial

2

0

High-throughput

0.328

High

884725

SYHM
Histidine--tRNA ligase, mitochondrial

2

0

High-throughput

0.328

High

1055374

APLP2
Amyloid beta precursor like protein 2

2

0

High-throughput

0.328

High

1060501

DPOE1
DNA polymerase epsilon catalytic subunit A

2

0

High-throughput

0.328

High

1085727

TBL3
Transducin beta-like protein 3

2

0

High-throughput

0.328

High

1212705

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.328

High

1226426

TBC9B
TBC1 domain family member 9B

2

0

High-throughput

0.328

High

1241650

ANM9
Protein arginine N-methyltransferase 9

2

0

High-throughput

0.328

High

1254319

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.328

High

1288107

OAF
Out at first protein homolog

2

0

High-throughput

0.328

High

1322670

RPTOR
Regulatory-associated protein of mTOR

2

0

High-throughput

0.328

High

1324691

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

2

0

High-throughput

0.328

High

1325554

LARG2
Xylosyl- and glucuronyltransferase LARGE2

2

0

High-throughput

0.328

High

1358488

CANT1
Soluble calcium-activated nucleotidase 1

2

0

High-throughput

0.328

High

1430049

INT2
Integrator complex subunit 2

2

0

High-throughput

0.328

High

1437620

NJMU
Protein Njmu-R1

2

0

High-throughput

0.328

High

1458405

S53A1
Solute carrier family 53 member 1

2

0

High-throughput

0.328

High

1460953

KDIS
Kinase D-interacting substrate of 220 kDa

2

0

High-throughput

0.328

High

1460956

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

2

0

High-throughput

0.328

High

592705

ITB4
Integrin beta-4

2

0

High-throughput

0.313

High

1234754

CK071
Uncharacterized protein C11orf71

1

0

High-throughput

0.282

High

253793

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.279

Low

292771

RENR
Renin receptor

1

0

High-throughput

0.279

Low

755431

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

0

High-throughput

0.279

Low

1108746

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.279

Low

1125084

RCN2
Reticulocalbin-2

1

0

High-throughput

0.279

Low

1131497

MBTP1
Membrane-bound transcription factor site-1 protease

1

0

High-throughput

0.279

Low

1143698

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1155283

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.279

Low

1272847

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

0

High-throughput

0.279

Low

1309655

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.279

Low

1312300

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.279

Low

1333366

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.279

Low

1339616

NLGN2
Neuroligin-2

1

0

High-throughput

0.279

Low

1385766

INT12
Integrator complex subunit 12

1

0

High-throughput

0.279

Low

1414303

ABHEA
Protein ABHD14A

1

0

High-throughput

0.279

Low

1415943

CINP
Cyclin-dependent kinase 2-interacting protein

1

0

High-throughput

0.279

Low

1418045

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

1448431

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

1449913

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.279

Low

1460002

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.279

Low

855793

CRK
Adapter molecule crk

1

0

High-throughput

0.249

Low

1358398

SCFD1
Sec1 family domain-containing protein 1

1

0

Small-scale

0.249

Low

212101

B4GT5
Beta-1,4-galactosyltransferase 5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025