HitPredict

Interactor 1: J3KNB8 (J3KNB8)
Mitogen-activated protein kinase kinase kinase 4
Gene: MAP3K4

Interactor 2: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1554 Hs			1 1132
+	Hs
		803832 M3K4_HUMAN (1-1554): 0: 2003: 96.58		BAG6_HUMAN (1-1132): 0: 597: 100.00
+	Hs
		803445 KS6A3_HUMAN (1226-1554): 9.68e-103: 348: 23.30		BAG6_HUMAN (1-1132): 0: 597: 100.00
+	Zm
		2191 A0A0B4J3D8_MAIZE (1279-1550): 1.9e-119: 384: 27.37		A0A1D6JMS0_MAIZE (1-503): 1.51e-26: 117: 15.13
+	Mm
		101422 KS6A3_MOUSE (1226-1554): 5.82e-103: 349: 23.30		F8VPR5_MOUSE (128-733): 2.34e-33: 142: 12.70
+	Hs
		850689 KS6A3_HUMAN (1226-1554): 9.68e-103: 348: 23.30		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		1071667 KS6A2_HUMAN (1277-1552): 1.63e-102: 347: 26.22		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		270431 KS6A5_HUMAN (1271-1554): 6.16e-102: 347: 27.76		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		1073459 KS6A1_HUMAN (1226-1554): 7.64e-100: 339: 23.30		CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25
+	Hs
		924126 M3K3_HUMAN (1275-1549): 1.43e-50: 192: 39.10		RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72
+	Hs
		924395 M3K3_HUMAN (1275-1549): 1.43e-50: 192: 39.10		RL40_HUMAN (17-87): 9.53e-28: 111: 34.72
+	Hs
		924221 M3K2_HUMAN (1289-1547): 1.2e-46: 180: 39.10		RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72
+	Hs
		924440 M3K2_HUMAN (1289-1547): 1.2e-46: 180: 39.10		RL40_HUMAN (17-87): 9.53e-28: 111: 34.72