HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: SPTB2 (Q62261)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)
Gene: Sptbn1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0044877 - protein-containing complex binding GO:0098794 - postsynapse and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 2363
+	Mm
		1112587 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		Q68FG2_MOUSE (2-2363): 0: 629: 61.10
+	Mm
		885077 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		ACTN4_MOUSE (53-525): 4.74e-121: 409: 47.58
+	Mm
		1112601 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		ACTN1_MOUSE (40-763): 7.59e-91: 319: 35.48
+	Mm
		561159 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		SPTN1_MOUSE (604-2355): 1.07e-63: 244: 20.52
+	Mm
		82757 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		B9EKJ1_MOUSE (604-2355): 3.04e-63: 242: 20.41
+	Mm
		1112660 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		MACF1_MOUSE (454-2218): 7.55e-47: 189: 12.25
+	Hs
		521541 GIT2_HUMAN (932-1139): 1.58e-73: 262: 31.98		ACTN1_HUMAN (40-763): 1.33e-92: 325: 35.35