HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: E41L3 (Q9WV92)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: Epb41l3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 929
+	Mm
		1112671 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		E41L1_MOUSE (1-928): 0: 618: 46.10
+	Mm
		250713 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		E41L2_MOUSE (1-918): 0: 615: 45.87
+	Hs
		1304057 AGAP2_HUMAN (1-1147): 0: 987: 94.10		E41L1_HUMAN (1-928): 0: 610: 45.89
+	Hs
		719593 AGAP2_HUMAN (1-1147): 0: 987: 94.10		MERL_HUMAN (98-690): 4.24e-124: 390: 21.18
+	Hs
		1357705 AGAP1_HUMAN (384-1145): 0: 713: 53.70		E41L3_HUMAN (521-929): 8.09e-82: 288: 80.05
+	Hs
		1020239 GIT1_HUMAN (932-1139): 4.84e-72: 258: 32.88		PTN13_HUMAN (13-913): 3.48e-135: 450: 15.19
+	Hs
		547273 ASAP1_HUMAN (746-1166): 2.43e-83: 297: 21.99		EZRI_HUMAN (114-659): 1.76e-123: 388: 22.36