HitPredict

Interactor 1: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Interactor 2: MEF2C (Q8CFN5)
Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C)
Gene: MEF2C

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10737771
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1115 Mm			1 474
+	Hs
		987234 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Mm
		1157743 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2C_MOUSE (1-474): 1.75e-102: 316: 100.00
+	Mm
		1112760 Q3UJF1_MOUSE (1-1115): 0: 796: 100.00		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Mm
		1144403 HDAC5_MOUSE (1-1115): 0: 788: 99.28		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Mm
		1112756 Q3UJF1_MOUSE (1-1115): 0: 796: 100.00		MEF2A_MOUSE (1-474): 8.21e-63: 213: 55.69
+	Hs
		880693 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Hs
		1059602 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2D_HUMAN (1-472): 1.34e-68: 229: 48.67
+	Hs
		968805 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		987233 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Mm
		1144399 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2D_MOUSE (1-472): 7.92e-68: 227: 49.13
+	Hs
		880729 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2D_HUMAN (1-472): 1.34e-68: 229: 48.67
+	Rn
		292567 HDAC4_RAT (3-1096): 0: 704: 54.56		MEF2D_RAT (1-472): 1.89e-65: 221: 48.46
+	Mm
		1141851 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2A_MOUSE (1-474): 8.21e-63: 213: 55.69
+	Hs
		880686 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		515573 HDAC4_HUMAN (3-1095): 0: 697: 55.51		SRF_HUMAN (2-376): 3.71e-53: 188: 18.62
+	Hs
		880687 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2B_HUMAN (1-428): 1.26e-46: 167: 32.01
+	Hs
		968804 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63
+	Hs
		987223 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		MEF2C_HUMAN (1-474): 2.31e-100: 310: 98.73
+	Hs
		968817 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2B_HUMAN (1-428): 1.26e-46: 167: 32.01
+	Hs
		968793 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		MEF2A_HUMAN (1-474): 5.08e-63: 214: 54.63