HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LAMC2 (Q13753)
Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma)
Gene: LAMC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1193
+	Hs
		666724 CUL3_HUMAN (1-768): 0: 943: 100.00		TENA_HUMAN (2-301): 6.54e-36: 151: 15.50
+	Hs
		1114643 CUL3_HUMAN (1-768): 0: 943: 100.00		NOTC3_HUMAN (282-743): 1.9e-32: 140: 14.34
+	Hs
		1113053 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMB3_HUMAN (8-188): 2.07e-30: 132: 31.94
+	Hs
		1047536 CUL3_HUMAN (1-768): 0: 943: 100.00		NOTC2_HUMAN (277-743): 3.21e-28: 126: 13.55
+	Hs
		644585 CUL3_HUMAN (1-768): 0: 943: 100.00		TENX_HUMAN (3-196): 1.25e-25: 117: 18.14
+	Hs
		857450 CUL3_HUMAN (1-768): 0: 943: 100.00		NOTC1_HUMAN (328-743): 1.31e-24: 114: 13.60
+	Hs
		1113223 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA3_HUMAN (460-698): 7.92e-13: 75.7: 19.75
+	Hs
		673767 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA1_HUMAN (187-420): 2.21e-12: 74.2: 11.60
+	Hs
		183248 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA5_HUMAN (1-126): 8.17e-11: 69.2: 17.69
+	Hs
		1113207 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMA4_HUMAN (959-1190): 8.67e-11: 68.8: 15.10
+	Hs
		462871 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMB1_HUMAN (69-337): 9.67e-11: 68.8: 13.19
+	Hs
		535837 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMC1_HUMAN (69-285): 6.19e-10: 66.1: 17.99
+	Hs
		937394 CUL3_HUMAN (1-768): 0: 943: 100.00		LAMB2_HUMAN (99-284): 5.5e-10: 66.1: 14.77
+	Hs
		1022536 CUL3_HUMAN (1-768): 0: 943: 100.00		PGBM_HUMAN (71-154): 8.4e-10: 65.7: 16.67
+	Hs
		535838 CUL4A_HUMAN (10-768): 0: 801: 38.32		LAMC1_HUMAN (69-285): 6.19e-10: 66.1: 17.99
+	Hs
		1022537 CUL4A_HUMAN (10-768): 0: 801: 38.32		PGBM_HUMAN (71-154): 8.4e-10: 65.7: 16.67
+	Hs
		462870 CUL1_HUMAN (18-768): 0: 709: 30.57		LAMB1_HUMAN (69-337): 9.67e-11: 68.8: 13.19