HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: RCBT1 (Q8NDN9)
RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1)
Gene: RCBTB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.946

Property	Details
Experiments	34878901, 35563538, 37495603, 37788672, 21145461, 19256485
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 531
+	Hs
		329142 CUL3_HUMAN (1-768): 0: 943: 100.00		RCBT2_HUMAN (1-531): 3.66e-163: 476: 69.87
+	Hs
		1112605 CUL1_HUMAN (18-768): 0: 709: 30.57		RCBT1_HUMAN (1-531): 2.9e-172: 498: 100.00
+	Hs
		1114596 CUL3_HUMAN (1-768): 0: 943: 100.00		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56
+	Hs
		1112922 CUL2_HUMAN (30-768): 0: 673: 26.17		RCBT1_HUMAN (1-531): 2.9e-172: 498: 100.00
+	Hs
		616314 CUL3_HUMAN (1-768): 0: 943: 100.00		RCC1_HUMAN (9-392): 2.79e-56: 196: 20.44
+	Hs
		1113790 CUL3_HUMAN (1-768): 0: 943: 100.00		NEK9_HUMAN (12-251): 1.18e-48: 182: 21.46
+	Hs
		1336713 CUL5_HUMAN (25-768): 0: 597: 23.77		RCBT1_HUMAN (1-531): 2.9e-172: 498: 100.00
+	Hs
		1113194 CUL3_HUMAN (1-768): 0: 943: 100.00		HERC1_HUMAN (4-146): 2.99e-28: 122: 28.28
+	Hs
		1115124 CUL4A_HUMAN (10-768): 0: 801: 38.32		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56
+	Hs
		1115482 CUL4B_HUMAN (5-768): 0: 796: 36.77		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56
+	Hs
		1114951 CUL4A_HUMAN (10-768): 0: 801: 38.32		NEK9_HUMAN (12-251): 1.18e-48: 182: 21.46
+	Hs
		1112769 CUL1_HUMAN (18-768): 0: 709: 30.57		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56
+	Hs
		1115469 CUL4B_HUMAN (5-768): 0: 796: 36.77		RCC2_HUMAN (176-415): 9.6e-35: 139: 19.75
+	Hs
		1113016 CUL2_HUMAN (30-768): 0: 673: 26.17		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56
+	Hs
		1371893 CUL5_HUMAN (25-768): 0: 597: 23.77		HERC5_HUMAN (12-424): 6.85e-69: 241: 21.56