HitPredict

Interactor 1: ZACN (Q401N2)
Ligand-gated cation channel ZACN (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) (Zinc-activated channel)
Gene: ZACN

Interactor 2: ASTRA (Q96CP6)
Protein Aster-A (GRAM domain-containing protein 1A)
Gene: GRAMD1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 724
+	Hs
		687008 ACHA3_HUMAN (29-373): 7.84e-139: 407: 19.78		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		798550 ACHA4_HUMAN (29-364): 6.43e-129: 386: 18.10		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		802371 5HT3A_HUMAN (24-332): 3.32e-125: 372: 24.23		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		570874 ACHB2_HUMAN (24-410): 1.43e-122: 366: 16.71		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		677162 ACHB4_HUMAN (14-361): 8.96e-123: 366: 16.90		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		1263260 5HT3C_HUMAN (20-357): 1.11e-119: 357: 24.01		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		1287054 ACHA9_HUMAN (7-337): 2.38e-116: 349: 17.54		ASTRA_HUMAN (1-724): 0: 915: 100.00
+	Hs
		798483 ACHA4_HUMAN (29-364): 6.43e-129: 386: 18.10		ASTRB_HUMAN (4-710): 0: 715: 47.20
+	Hs
		802328 5HT3A_HUMAN (24-332): 3.32e-125: 372: 24.23		ASTRB_HUMAN (4-710): 0: 715: 47.20