Protein: CCNH
Cyclin-H (MO15-associated protein) (p34) (p37)

Gene: CCNH
Organism: Homo sapiens
Interactions: 81
UniProt ID: P51946

Gene Ontology (top 5):
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

841100

CDK7
Cyclin-dependent kinase 7

25

20

Small-scale

0.992

High

625251

CDK2
Cyclin-dependent kinase 2

9

20

Small-scale

0.973

High

851197

CDK3
Cyclin-dependent kinase 3

2

20

High-throughput

0.783

High

851198

CDK6
Cyclin-dependent kinase 6

2

20

High-throughput

0.783

High

584570

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

10

4

Small-scale

0.749

High

851193

MAT1
CDK-activating kinase assembly factor MAT1

7

5

Small-scale

0.746

High

851212

CDK20
Cyclin-dependent kinase 20

1

20

Small-scale

0.713

High

637363

PSA1
Proteasome subunit alpha type-1

4

2

High-throughput

0.705

High

574140

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

4

2

Small-scale

0.694

High

624415

CCNC
Cyclin-C

1

10

Small-scale

0.692

High

826245

CDK8
Cyclin-dependent kinase 8

1

20

Small-scale

0.692

High

125865

CDC7
Cell division cycle 7-related protein kinase

1

20

High-throughput

0.691

High

538500

CCNB1
G2/mitotic-specific cyclin-B1

1

6

High-throughput

0.691

High

697727

TF2H1
General transcription factor IIH subunit 1

5

1

Small-scale

0.691

High

851229

DUS12
Dual specificity protein phosphatase 12

4

0

High-throughput

0.668

High

659913

ERCC5
DNA excision repair protein ERCC-5

3

7

High-throughput

0.667

High

851201

GOGA2
Golgin subfamily A member 2

5

2

High-throughput

0.657

High

369219

ESR1
Estrogen receptor

3

19

Small-scale

0.633

High

851205

TF2H2
General transcription factor IIH subunit 2

3

1

Small-scale

0.633

High

683912

1433S
14-3-3 protein sigma

2

4

High-throughput

0.628

High

851202

LIPA1
Liprin-alpha-1

3

1

High-throughput

0.617

High

64094

CPS4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein

3

1

High-throughput

0.609

High

851217

TBC15
TBC1 domain family member 15

3

2

High-throughput

0.609

High

235489

VINEX
Vinexin

2

5

High-throughput

0.606

High

551096

ITF2
Transcription factor 4

2

1

High-throughput

0.606

High

843118

TCPD
T-complex protein 1 subunit delta

2

3

High-throughput

0.606

High

851208

GRAP1
GRIP1-associated protein 1

2

2

High-throughput

0.606

High

851231

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.606

High

624819

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

5

Small-scale

0.602

High

346280

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.595

High

851214

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

851221

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

851226

GO45
Golgin-45

2

0

High-throughput

0.580

High

851209

KLC3
Kinesin light chain 3

2

5

High-throughput

0.573

High

154939

NDC80
Kinetochore protein NDC80 homolog

1

3

High-throughput

0.573

High

851203

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

High-throughput

0.573

High

851194

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.567

High

386353

P53
Cellular tumor antigen p53

1

9

Small-scale

0.561

High

487251

ANDR
Androgen receptor

1

19

Small-scale

0.561

High

487926

RARA
Retinoic acid receptor alpha

1

15

Small-scale

0.561

High

808056

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

Small-scale

0.561

High

851207

RHOH
Rho-related GTP-binding protein RhoH

2

1

High-throughput

0.553

High

851215

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

3

High-throughput

0.553

High

500361

RARB
Retinoic acid receptor beta

1

15

High-throughput

0.541

High

851195

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.541

High

241285

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.536

High

257333

CNOT3
CCR4-NOT transcription complex subunit 3

1

2

High-throughput

0.536

High

538752

HXB1
Homeobox protein Hox-B1

1

5

High-throughput

0.536

High

851211

CC170
Coiled-coil domain-containing protein 170

1

2

High-throughput

0.523

High

851223

HTF4
Transcription factor 12

1

1

High-throughput

0.515

High

245673

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

781529

CETN2
Centrin-2

1

0

High-throughput

0.513

High

851210

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.513

High

851225

BC11B
B-cell lymphoma/leukemia 11B

1

0

High-throughput

0.513

High

123880

SPT5H
Transcription elongation factor SPT5

1

4

Small-scale

0.501

High

676839

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

Small-scale

0.501

High

851218

TF2H4
General transcription factor IIH subunit 4

1

1

Small-scale

0.500

High

851206

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.494

High

300993

ABLM3
Actin-binding LIM protein 3

1

1

High-throughput

0.489

High

851200

LMNB2
Lamin-B2

1

3

High-throughput

0.489

High

851224

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

5

High-throughput

0.481

High

244145

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

552284

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

650725

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

708845

MCM7
DNA replication licensing factor MCM7

1

5

Small-scale

0.479

High

720022

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

749254

BRCA1
Breast cancer type 1 susceptibility protein

1

5

Small-scale

0.479

High

851204

MTA1
Metastasis-associated protein MTA1

1

1

Small-scale

0.479

High

851219

FUBP1
Far upstream element-binding protein 1

1

1

Small-scale

0.479

High

851228

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

851222

RADIL
Ras-associating and dilute domain-containing protein

1

2

High-throughput

0.470

High

851220

DDT4L
DNA damage-inducible transcript 4-like protein

1

1

High-throughput

0.470

High

851196

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.437

High

851199

XPC
DNA repair protein complementing XP-C cells

1

0

Small-scale

0.426

High

851230

MTMR7
Myotubularin-related protein 7

4

0

High-throughput

0.361

High

224915

ZNRD2
Protein ZNRD2

3

0

High-throughput

0.354

High

851227

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

211355

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

851216

IL17D
Interleukin-17D

1

0

High-throughput

0.279

Low

310920

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.268

Low

851213

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024