HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25189618, 34026424
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 1048
+	Hs
		1115048 CUL4A_HUMAN (161-913): 0: 957: 81.83		SP130_HUMAN (1-1048): 3.89e-131: 425: 100.00
+	Hs
		76111 CUL4B_HUMAN (1-913): 0: 1185: 100.00		B4DET5_HUMAN (15-788): 4.79e-24: 111: 12.58
+	Hs
		1115326 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TITIN_HUMAN (8-968): 5.68e-09: 62.8: 8.97
+	Hs
		1112706 CUL1_HUMAN (213-913): 0: 779: 30.16		SP130_HUMAN (1-1048): 3.89e-131: 425: 100.00
+	Hs
		1112986 CUL2_HUMAN (205-913): 0: 747: 27.53		SP130_HUMAN (1-1048): 3.89e-131: 425: 100.00
+	Hs
		1114963 CUL4A_HUMAN (161-913): 0: 957: 81.83		TITIN_HUMAN (8-968): 5.68e-09: 62.8: 8.97
+	Hs
		1113479 CUL3_HUMAN (186-913): 0: 854: 37.19		SRCAP_HUMAN (4-770): 3.4e-23: 109: 12.78
+	Hs
		1113742 CUL3_HUMAN (186-913): 0: 854: 37.19		KMT2C_HUMAN (10-987): 6.15e-18: 92.4: 10.33
+	Hs
		1113373 CUL3_HUMAN (186-913): 0: 854: 37.19		MUC17_HUMAN (1-665): 3.54e-16: 86.6: 11.00
+	Hs
		1113526 CUL3_HUMAN (186-913): 0: 854: 37.19		TICRR_HUMAN (13-804): 3.89e-15: 82.9: 15.05
+	Hs
		1114070 CUL3_HUMAN (186-913): 0: 854: 37.19		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Hs
		1113861 CUL3_HUMAN (186-913): 0: 854: 37.19		TITIN_HUMAN (8-968): 5.68e-09: 62.8: 8.97
+	Dm
		1465697 Q9V475_DROME (191-913): 0: 802: 37.48		Q9VLS7_DROME (118-944): 4.26e-15: 82.8: 10.04
+	Hs
		1112933 CUL2_HUMAN (205-913): 0: 747: 27.53		TITIN_HUMAN (8-968): 5.68e-09: 62.8: 8.97