HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: CC85A (Q96PX6)
Coiled-coil domain-containing protein 85A
Gene: CCDC85A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.560

Property	Details
Experiments	32296183, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1128 Hs			1 553
+	Hs
		1053272 Q05BL1_HUMAN (91-1128): 2.69e-149: 476: 100.00		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1396245 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1400297 BARD1_HUMAN (675-1036): 6.11e-46: 180: 17.37		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1400301 TNKS2_HUMAN (827-1127): 1.75e-41: 168: 11.11		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		66609 ASPP2_HUMAN (1-1128): 0: 588: 100.00		CC85C_HUMAN (34-268): 7.86e-76: 248: 51.18
+	Hs
		1115519 ASPP2_HUMAN (1-1128): 0: 588: 100.00		CC85B_HUMAN (36-175): 2.74e-51: 176: 50.00
+	Hs
		66651 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		CC85C_HUMAN (34-268): 7.86e-76: 248: 51.18
+	Hs
		1154565 ASPP1_HUMAN (1-1128): 1.03e-130: 427: 45.38		CC85B_HUMAN (36-175): 2.74e-51: 176: 50.00
+	Dm
		1484280 Q9W2J2_DROME (126-1123): 1.12e-76: 275: 27.13		Q9VQK1_DROME (71-219): 8.48e-60: 210: 51.68