Protein: CC85C
Coiled-coil domain-containing protein 85C

Gene: CC85C, CCDC85C
Organism: Homo sapiens
Interactions: 129
UniProt ID: A6NKD9

Gene Ontology (top 5):
GO:0005912 - adherens junction
GO:0005923 - bicellular tight junction
GO:0007219 - Notch signaling pathway
GO:0008283 - cell population proliferation
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

66584

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

7

6

High-throughput

0.747

High

66596

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

6

High-throughput

0.737

High

66586

YAP1
Transcriptional coactivator YAP1

6

3

Small-scale

0.728

High

66610

SETB1
Histone-lysine N-methyltransferase SETDB1

4

1

High-throughput

0.630

High

66597

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

3

6

High-throughput

0.619

High

66561

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

3

2

High-throughput

0.609

High

66573

CRYAB
Alpha-crystallin B chain

3

3

High-throughput

0.609

High

66672

MBIP1
MAP3K12-binding inhibitory protein 1

3

1

High-throughput

0.609

High

66630

SKA3
Spindle and kinetochore-associated protein 3

2

1

High-throughput

0.574

High

66649

CC136
Coiled-coil domain-containing protein 136

2

1

High-throughput

0.574

High

66651

ASPP1
Apoptosis-stimulating of p53 protein 1

2

8

High-throughput

0.574

High

66556

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

1

Small-scale

0.558

High

66569

KDM4B
Lysine-specific demethylase 4B

2

1

High-throughput

0.558

High

66563

ZNRD2
Protein ZNRD2

2

1

High-throughput

0.549

High

66678

PNMA2
Paraneoplastic antigen Ma2

2

2

High-throughput

0.549

High

66609

ASPP2
Apoptosis-stimulating of p53 protein 2

1

9

High-throughput

0.536

High

66654

CC85A
Coiled-coil domain-containing protein 85A

1

2

High-throughput

0.536

High

66680

NINL
Ninein-like protein

2

1

High-throughput

0.533

High

66598

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

66595

1433G
14-3-3 protein gamma

1

4

High-throughput

0.506

High

66604

1433F
14-3-3 protein eta

1

4

High-throughput

0.506

High

66467

RASFA
Ras association domain-containing protein 10

1

2

High-throughput

0.489

High

66566

RASF9
Ras association domain-containing protein 9

1

5

High-throughput

0.489

High

66568

KRT38
Keratin, type I cuticular Ha8

1

5

High-throughput

0.489

High

66581

1433B
14-3-3 protein beta/alpha

1

4

High-throughput

0.489

High

66589

CEBPG
CCAAT/enhancer-binding protein gamma

1

3

High-throughput

0.489

High

66600

1433Z
14-3-3 protein zeta/delta

1

4

High-throughput

0.489

High

66629

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.489

High

66635

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.489

High

66638

SYTL5
Synaptotagmin-like protein 5

1

2

High-throughput

0.489

High

66642

ING5
Inhibitor of growth protein 5

1

1

High-throughput

0.489

High

66669

SAYS1
SAYSvFN domain-containing protein 1

1

1

High-throughput

0.489

High

66583

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

66590

AFAD
Afadin

1

1

High-throughput

0.479

High

66592

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.479

High

66593

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

66605

ZO1
Tight junction protein 1

1

1

High-throughput

0.479

High

66640

PARD3
Partitioning defective 3 homolog

1

3

High-throughput

0.479

High

66661

WWTR1
WW domain-containing transcription regulator protein 1

1

3

High-throughput

0.479

High

66674

ZO2
Tight junction protein 2

1

1

High-throughput

0.479

High

66558

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

66564

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

66567

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

66577

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

66582

CTNA1
Catenin alpha-1

1

0

High-throughput

0.458

High

66588

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.458

High

66591

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

66613

OCLN
Occludin

1

0

High-throughput

0.458

High

66620

FTM
Protein fantom

1

0

High-throughput

0.458

High

66679

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

66555

RHOD
Rho-related GTP-binding protein RhoD

1

2

High-throughput

0.437

High

66571

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.437

High

66574

VIME
Vimentin

1

3

High-throughput

0.437

High

66575

FGFR1
Fibroblast growth factor receptor 1

1

1

High-throughput

0.437

High

66579

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.437

High

66585

PERI
Peripherin

1

3

High-throughput

0.437

High

66594

RND3
Rho-related GTP-binding protein RhoE

1

2

High-throughput

0.437

High

66601

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

66614

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

1

High-throughput

0.437

High

66621

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.437

High

66633

NIN
Ninein

1

1

High-throughput

0.437

High

66639

FBF1
Fas-binding factor 1

1

1

High-throughput

0.437

High

66652

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.437

High

66653

SCLT1
Sodium channel and clathrin linker 1

1

1

High-throughput

0.437

High

66659

UNK
RING finger protein unkempt homolog

1

1

High-throughput

0.437

High

66663

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

1

Small-scale

0.437

High

66664

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

66671

LATS2
Serine/threonine-protein kinase LATS2

1

1

High-throughput

0.437

High

66553

F5GX28
Lysine-specific demethylase 4B

1

1

High-throughput

0.407

High

66578

PACA
Pituitary adenylate cyclase-activating polypeptide

1

1

High-throughput

0.407

High

66636

RASF8
Ras association domain-containing protein 8

1

5

High-throughput

0.407

High

66570

GGPPS
Geranylgeranyl pyrophosphate synthase

3

0

High-throughput

0.347

High

66603

PSG9
Pregnancy-specific beta-1-glycoprotein 9

3

0

High-throughput

0.347

High

66617

ARH
Low density lipoprotein receptor adapter protein 1

3

0

High-throughput

0.347

High

66618

SUSD4
Sushi domain-containing protein 4

3

0

High-throughput

0.347

High

66572

CD4
T-cell surface glycoprotein CD4

2

0

High-throughput

0.328

High

66606

SCRN1
Secernin-1

2

0

High-throughput

0.328

High

66628

EGFL6
Epidermal growth factor-like protein 6

2

0

High-throughput

0.328

High

66631

DAAF8
Dynein axonemal assembly factor 8

2

0

High-throughput

0.328

High

66645

NGN1
Neurogenin-1

2

0

High-throughput

0.313

High

66611

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.305

High

66560

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.279

Low

66562

EXTL3
Exostosin-like 3

1

0

High-throughput

0.279

Low

66576

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

66580

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.279

Low

66599

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.279

Low

66602

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

66612

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.279

Low

66615

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

66622

CD109
CD109 antigen

1

0

High-throughput

0.279

Low

66643

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

66646

SPSB4
SPRY domain-containing SOCS box protein 4

1

0

High-throughput

0.279

Low

66656

GDF15
Growth/differentiation factor 15

1

0

High-throughput

0.279

Low

66658

OSBL7
Oxysterol-binding protein-related protein 7

1

0

High-throughput

0.279

Low

66662

IQCN
IQ domain-containing protein N

1

0

High-throughput

0.279

Low

66666

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.279

Low

66554

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.269

Low

66667

OTOF
Otoferlin

1

0

High-throughput

0.269

Low

66644

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.251

Low

66557

PLK4
Serine/threonine-protein kinase PLK4

1

0

Small-scale

0.249

Low

66559

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

66565

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.249

Low

66587

PAXI
Paxillin

1

0

High-throughput

0.249

Low

66607

SQSTM
Sequestosome-1

1

0

High-throughput

0.249

Low

66608

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.249

Low

66616

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.249

Low

66619

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

66623

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

66624

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.249

Low

66625

CNTRL
Centriolin

1

0

High-throughput

0.249

Low

66626

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

66632

CNTRB
Centrobin

1

0

High-throughput

0.249

Low

66634

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

66637

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.249

Low

66647

PF21A
PHD finger protein 21A

1

0

High-throughput

0.249

Low

66648

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

66655

CEP89
Centrosomal protein of 89 kDa

1

0

High-throughput

0.249

Low

66657

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

0

High-throughput

0.249

Low

66660

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.249

Low

66665

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

66668

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.249

Low

66670

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.249

Low

66675

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

66676

ANC2
Anaphase-promoting complex subunit 2

1

0

High-throughput

0.249

Low

66677

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

66627

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.232

Low

66641

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

0

High-throughput

0.232

Low

66650

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

66673

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025