HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: PP6R1 (Q7TSI3)
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)
Gene: Ppp6r1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 856
+	Mm
		1116046 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PP6R2_MOUSE (1-853): 0: 860: 40.69
+	Hs
		1237562 ANR44_HUMAN (2-537): 4.52e-90: 319: 14.66		PP6R1_HUMAN (1-856): 0: 884: 83.77
+	Hs
		257199 ANR44_HUMAN (2-537): 4.52e-90: 319: 14.66		PP6R2_HUMAN (1-852): 0: 870: 42.08
+	Hs
		1239519 ANR52_HUMAN (14-494): 3.38e-78: 284: 16.60		PP6R1_HUMAN (1-856): 0: 884: 83.77
+	Hs
		257200 ANR52_HUMAN (14-494): 3.38e-78: 284: 16.60		PP6R2_HUMAN (1-852): 0: 870: 42.08
+	Hs
		1330883 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		PP6R1_HUMAN (1-856): 0: 884: 83.77
+	Hs
		883672 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		PP6R1_HUMAN (1-856): 0: 884: 83.77
+	Hs
		1126010 ANR44_HUMAN (2-537): 4.52e-90: 319: 14.66		PP6R3_HUMAN (1-852): 0: 796: 45.28
+	Hs
		1126012 ANR52_HUMAN (14-494): 3.38e-78: 284: 16.60		PP6R3_HUMAN (1-852): 0: 796: 45.28
+	Hs
		167044 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		PP6R1_HUMAN (1-856): 0: 884: 83.77
+	Hs
		166864 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		PP6R2_HUMAN (1-852): 0: 870: 42.08
+	Hs
		166945 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		PP6R3_HUMAN (1-852): 0: 796: 45.28
+	Mm
		1116020 SHAN3_MOUSE (1-1730): 0: 626: 100.00		Q8C3X1_MOUSE (1-213): 8.95e-102: 317: 58.69