Protein: HIPK4
Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)

Gene: HIPK4
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q8NE63

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

461719

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.789

High

468605

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.789

High

521391

ARAF
Serine/threonine-protein kinase A-Raf

1

20

High-throughput

0.691

High

856815

BAG6
Large proline-rich protein BAG6

1

18

High-throughput

0.691

High

1106004

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

18

High-throughput

0.691

High

1158435

CDC37
Hsp90 co-chaperone Cdc37

1

11

High-throughput

0.691

High

1337133

ZN281
Zinc finger protein 281

1

5

High-throughput

0.691

High

1337124

APBP2
Amyloid protein-binding protein 2

2

9

High-throughput

0.633

High

401165

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

543240

UBL4A
Ubiquitin-like protein 4A

1

13

High-throughput

0.618

High

701871

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.618

High

1141587

OZF
Zinc finger protein OZF

1

0

High-throughput

0.586

High

1145624

RCN1
Reticulocalbin-1

1

12

High-throughput

0.553

High

229045

AKAP8
A-kinase anchor protein 8

1

3

High-throughput

0.536

High

339540

ACSL3
Fatty acid CoA ligase Acsl3

1

3

High-throughput

0.536

High

420624

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

9

High-throughput

0.536

High

565979

EF2
Elongation factor 2

1

11

High-throughput

0.536

High

756277

MCM7
DNA replication licensing factor MCM7

1

16

High-throughput

0.536

High

882042

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.536

High

1032508

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

10

High-throughput

0.536

High

1066404

RBBP4
Histone-binding protein RBBP4

1

10

High-throughput

0.536

High

1131780

LBR
Delta(14)-sterol reductase LBR

1

2

High-throughput

0.536

High

1337126

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

2

High-throughput

0.536

High

1337127

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.536

High

1337130

TECR
Very-long-chain enoyl-CoA reductase

1

2

High-throughput

0.536

High

1337131

DIC
Mitochondrial dicarboxylate carrier

1

13

High-throughput

0.536

High

1337134

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

2

High-throughput

0.536

High

1337135

YTHD2
YTH domain-containing family protein 2

1

10

High-throughput

0.536

High

460848

CATB
Cathepsin B

1

2

High-throughput

0.489

High

1337123

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

11

High-throughput

0.489

High

1337125

SFXN2
Sideroflexin-2

1

1

High-throughput

0.489

High

730776

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

842808

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

14

High-throughput

0.479

High

971796

1433E
14-3-3 protein epsilon

1

20

High-throughput

0.479

High

1337129

WDR6
tRNA

1

20

High-throughput

0.479

High

1330260

ARF
Tumor suppressor ARF

1

1

High-throughput

0.445

High

1311582

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.437

High

162243

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.407

High

903738

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.407

High

1337132

NOP58
Nucleolar protein 58

1

3

High-throughput

0.407

High

1210354

NU188
Nucleoporin NUP188

1

0

High-throughput

0.279

Low

1337128

TRABD
TraB domain-containing protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025