Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: CNKR2 (Q80YA9)
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)
Gene: Cnksr2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ_6, PDZ~SAM_1, SAM_1~SAM_1, PDZ~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0045211 - postsynaptic membrane
GO:0098978 - glutamatergic synapse
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 1032
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+ Ce

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Last updated: 15 Jul 2024