HitPredict

Interactor 1: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Interactor 2: Q9ESH1 (Q9ESH1)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10)
Gene: Psmd4

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20178748
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 415 Rn			1 377
+	Hs
		872242 RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Hs
		872125 RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Hs
		874198 UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Zm
		22892 A0A1D6I428_MAIZE (1-415): 7.52e-108: 327: 26.82		A0A1D6KBS7_MAIZE (1-338): 5.19e-131: 380: 37.28
+	At
		874017 RD23C_ARATH (1-415): 6.78e-103: 313: 35.42		PSMD4_ARATH (1-377): 1.15e-134: 391: 40.73
+	At
		874019 RD23B_ARATH (1-415): 1.23e-101: 308: 35.06		PSMD4_ARATH (1-377): 1.15e-134: 391: 40.73
+	At
		874018 RD23A_ARATH (1-415): 1.72e-98: 300: 33.73		PSMD4_ARATH (1-377): 1.15e-134: 391: 40.73
+	Hs
		874195 UBQL2_HUMAN (1-363): 1.82e-46: 170: 12.22		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Xl
		1118797 Q9PVN8_XENLA (22-363): 1e-49: 178: 14.13		Q4V845_XENLA (1-364): 0: 510: 91.21
+	Dm
		874035 Q9V3W9_DROME (1-414): 3.39e-85: 267: 37.42		PSMD4_DROME (1-359): 9.68e-146: 419: 56.58
+	At
		874016 RD23D_ARATH (1-415): 2.49e-92: 284: 29.98		PSMD4_ARATH (1-377): 1.15e-134: 391: 40.73
+	Hs
		874185 UBQL4_HUMAN (1-363): 9.84e-41: 154: 14.29		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Hs
		874069 RL40_HUMAN (1-112): 6.75e-40: 140: 24.11		PSMD4_HUMAN (1-364): 0: 519: 98.90
+	Dm
		874046 Q9VWD9_DROME (1-363): 1.21e-59: 204: 13.70		PSMD4_DROME (1-359): 9.68e-146: 419: 56.58
+	Dm
		874047 Q9VXF9_DROME (1-412): 2.46e-53: 185: 13.94		PSMD4_DROME (1-359): 9.68e-146: 419: 56.58
+	At
		874024 DSK2B_ARATH (1-413): 1.88e-62: 212: 14.34		PSMD4_ARATH (1-377): 1.15e-134: 391: 40.73
+	Sc
		697082 RAD23_YEAST (1-413): 1.14e-72: 234: 26.82		RPN10_YEAST (1-224): 2.35e-97: 292: 49.15
+	Ce
		247744 Q23451_CAEEL (1-414): 1.22e-48: 170: 26.68		PSMD4_CAEEL (1-372): 8.57e-112: 332: 44.74
+	Sc
		756974 DSK2_YEAST (1-354): 3.82e-40: 148: 18.26		RPN10_YEAST (1-224): 2.35e-97: 292: 49.15
+	Sp
		293402 RL402_SCHPO (1-111): 2.68e-36: 131: 22.52		RPN10_SCHPO (1-245): 3.25e-102: 303: 45.75