HitPredict

Interactor 1: Q4V845 (Q4V845)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10)
Gene: psmd4.S

Interactor 2: BAG6A (Q9YHD3)
Large proline-rich protein bag6-A (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-A) (Protein Scythe)
Gene: Bag6-a

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16336274
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 376 Xl			1 1135
+	Hs
		803454 PSMD4_HUMAN (1-364): 0: 517: 91.48		BAG6_HUMAN (1-1135): 6.17e-134: 437: 47.44
+	Hs
		475528 PSMD4_HUMAN (1-364): 0: 517: 91.48		UBC_HUMAN (7-257): 2.42e-35: 146: 21.83
+	Mm
		192426 PSMD4_MOUSE (1-370): 2.8e-179: 504: 88.65		UBC_MOUSE (7-294): 2.38e-36: 149: 20.34
+	Hs
		474970 PSMD4_HUMAN (1-364): 0: 517: 91.48		UBB_HUMAN (7-80): 3.66e-23: 101: 37.33
+	Hs
		56649 PIPSL_HUMAN (3-364): 1.47e-179: 522: 84.53		SRCAP_HUMAN (25-595): 1.91e-10: 67.9: 8.58
+	Hs
		874068 PSMD4_HUMAN (1-364): 0: 517: 91.48		RS27A_HUMAN (7-77): 3.09e-12: 67.5: 38.89
+	Hs
		874069 PSMD4_HUMAN (1-364): 0: 517: 91.48		RL40_HUMAN (7-77): 1.55e-12: 67.5: 38.89
+	Dm
		547908 PSMD4_DROME (1-375): 7.44e-155: 443: 54.91		RS27A_DROME (7-77): 3.09e-12: 67.5: 38.89
+	At
		874015 PSMD4_ARATH (1-375): 3.12e-137: 398: 40.70		UBQ3_ARATH (7-82): 2.2e-21: 98.3: 36.36
+	Sc
		477277 RPN10_YEAST (1-224): 3.07e-98: 294: 49.15		UBI4P_YEAST (7-176): 8.19e-29: 121: 25.73
+	Sp
		293402 RPN10_SCHPO (1-245): 5.58e-104: 308: 45.75		RL402_SCHPO (7-77): 1.5e-12: 67.5: 37.50