HitPredict

Interactor 1: K9JA46 (K9JA46)
Heat shock protein HSP 90-alpha
Gene: EL52

Interactor 2: FKBP6 (O75344)
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36)
Gene: FKBP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~HSP90
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 327
+	Hs
		259914 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00
+	Hs
		111936 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (2-327): 4.29e-73: 234: 23.33
+	Hs
		431755 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (2-327): 4.29e-73: 234: 23.33
+	Mm
		432409 HS90A_MOUSE (1-732): 0: 1083: 97.82		FKBP4_MOUSE (2-327): 6.15e-73: 234: 23.64
+	Hs
		259915 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP6_HUMAN (1-327): 4.19e-82: 253: 100.00
+	Hs
		111937 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (2-327): 2.72e-66: 216: 22.73
+	Hs
		431818 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (2-327): 2.72e-66: 216: 22.73
+	Hs
		438089 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP4_HUMAN (2-327): 4.29e-73: 234: 23.33
+	Hs
		431850 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP8_HUMAN (1-319): 8.64e-60: 198: 23.80
+	Hs
		432312 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIPL1_HUMAN (36-317): 4.56e-56: 188: 17.90
+	Hs
		438136 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP5_HUMAN (2-327): 2.72e-66: 216: 22.73
+	Hs
		111929 K9JA46_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (33-316): 2.17e-53: 180: 17.39
+	Hs
		118674 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (33-316): 2.17e-53: 180: 17.39
+	Hs
		111943 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (8-316): 4.28e-48: 166: 18.10
+	Hs
		432338 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (8-316): 4.28e-48: 166: 18.10
+	Hs
		432058 HS90A_HUMAN (1-732): 0: 1087: 100.00		TTC9C_HUMAN (164-316): 3.12e-47: 158: 28.07
+	Hs
		118678 HS90B_HUMAN (19-732): 0: 1059: 86.13		AIP_HUMAN (33-316): 2.17e-53: 180: 17.39
+	Hs
		431781 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPID_HUMAN (89-316): 1.32e-41: 149: 22.65
+	Hs
		431721 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKB1A_HUMAN (37-139): 1.41e-37: 131: 35.58
+	Hs
		438106 HS90B_HUMAN (19-732): 0: 1059: 86.13		PPID_HUMAN (89-316): 1.32e-41: 149: 22.65