Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB
Interactor 2: KS6A2 (Q15349)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: RPS6KA2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.77 | 1.00 | 0.883 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31678930, 30126976, 29144123 |
| Identification Methods | proximity labelling technology, anti tag coimmunoprecipitation, isothermal titration calorimetry, microscale thermophoresis, pull down, nuclear magnetic resonance, p8 filamentous phage display |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~Pkinase |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043065 - positive regulation of apoptotic process |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
