HitPredict

Interactor 1: PP6R3 (Q5H9R7)
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
Gene: PPP6R3

Interactor 2: BRSK1 (Q8TDC3)
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)
Gene: BRSK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 873 Hs			1 778
+	Hs
		1126004 PP6R3_HUMAN (1-873): 0: 854: 100.00		BRSK2_HUMAN (25-778): 5.6e-173: 517: 71.28
+	Hs
		1254751 PP6R1_HUMAN (1-872): 0: 670: 44.00		BRSK1_HUMAN (1-778): 0: 646: 100.00
+	Hs
		871402 PP6R3_HUMAN (1-873): 0: 854: 100.00		AAPK2_HUMAN (26-559): 4.11e-145: 438: 30.43
+	Hs
		257161 PP6R2_HUMAN (1-870): 0: 766: 45.79		MARK3_HUMAN (11-711): 5.7e-165: 497: 26.98
+	Hs
		257192 PP6R2_HUMAN (1-870): 0: 766: 45.79		MARK2_HUMAN (9-711): 3.43e-154: 470: 27.45
+	Hs
		257229 PP6R2_HUMAN (1-870): 0: 766: 45.79		MARK1_HUMAN (4-711): 2.2e-149: 458: 26.05
+	Mm
		1149051 PP6R1_MOUSE (1-873): 0: 672: 43.81		BRSK2_MOUSE (25-778): 1.73e-174: 520: 71.15