HitPredict - High confidence protein-protein interactions

Interactor 1: TLR9 (Q5I2M5)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Interactor 2: TLR9 (Q5I2M5)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Interacting Pfam domains	LRR_1~LRR_1, LRR_1~LRR_8, LRR_12~LRR_8, LRR_8~LRR_8
Common GO terms	GO:0002218 - activation of innate immune response GO:0002224 - toll-like receptor signaling pathway GO:0002639 - positive regulation of immunoglobulin production GO:0005764 - lysosome GO:0005768 - endosome and 23 others more... GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0007249 - canonical NF-kappaB signal transduction GO:0030890 - positive regulation of B cell proliferation GO:0032009 - early phagosome GO:0032727 - positive regulation of interferon-alpha production GO:0032728 - positive regulation of interferon-beta production GO:0032729 - positive regulation of type II interferon production GO:0032755 - positive regulation of interleukin-6 production GO:0034165 - positive regulation of toll-like receptor 9 signaling pathway GO:0035197 - siRNA binding GO:0036019 - endolysosome GO:0038187 - pattern recognition receptor activity GO:0042803 - protein homodimerization activity GO:0043410 - positive regulation of MAPK cascade GO:0045087 - innate immune response GO:0045322 - unmethylated CpG binding GO:0045577 - regulation of B cell differentiation GO:0050871 - positive regulation of B cell activation GO:0051092 - positive regulation of NF-kappaB transcription factor activity GO:0051607 - defense response to virus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	1029
Bt

1	1029

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Last updated: 15 Jul 2024