Protein: JIP4
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)

Gene: JIP4, SPAG9
Organism: Homo sapiens
Interactions: 164
UniProt ID: O60271

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0001933 - negative regulation of protein phosphorylation
GO:0005078 - MAP-kinase scaffold activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

229655

ARF6
ADP-ribosylation factor 6

4

9

Small-scale

0.900

High

229751

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

2

17

High-throughput

0.811

High

229607

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

2

16

Small-scale

0.768

High

229648

PLK1
Serine/threonine-protein kinase PLK1

7

2

Small-scale

0.750

High

229721

ARL5B
ADP-ribosylation factor-like protein 5B

1

10

High-throughput

0.691

High

229624

NFKB1
Nuclear factor NF-kappa-B p105 subunit

4

7

High-throughput

0.687

High

62121

RCCD1
RCC1 domain-containing protein 1

3

4

High-throughput

0.675

High

229657

ARF1
ADP-ribosylation factor 1

1

9

Small-scale

0.647

High

229701

MREG
Melanoregulin

3

0

High-throughput

0.638

High

134430

PODXL
Podocalyxin

2

2

High-throughput

0.628

High

229617

TPM3
Tropomyosin alpha-3 chain

2

8

High-throughput

0.628

High

229618

SYPH
Synaptophysin

2

1

High-throughput

0.628

High

229619

TPM1
Tropomyosin alpha-1 chain

2

8

High-throughput

0.628

High

229632

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.618

High

229664

ARL16
ADP-ribosylation factor-like protein 16

1

16

High-throughput

0.618

High

157100

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

2

0

High-throughput

0.602

High

229623

LEUK
Leukosialin

2

0

High-throughput

0.602

High

229669

SCRB2
Lysosome membrane protein 2

2

0

High-throughput

0.602

High

229702

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

0

High-throughput

0.602

High

229651

RAB8A
Ras-related protein Rab-8A

2

10

Small-scale

0.588

High

229612

ZBED1
E3 SUMO-protein ligase ZBED1

2

1

High-throughput

0.574

High

229673

SMCO1
Single-pass membrane and coiled-coil domain-containing protein 1

2

1

High-throughput

0.574

High

229723

MERB1
bMERB domain-containing protein 1

2

1

High-throughput

0.574

High

229703

ARL10
ADP-ribosylation factor-like protein 10

1

13

High-throughput

0.553

High

229665

TP53B
TP53-binding protein 1

1

7

High-throughput

0.552

High

156629

PPE2
Serine/threonine-protein phosphatase with EF-hands 2

1

10

High-throughput

0.536

High

213182

SNG2
Synaptogyrin-2

1

1

High-throughput

0.536

High

213416

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

6

High-throughput

0.536

High

229611

TSN15
Tetraspanin-15

1

7

High-throughput

0.536

High

229625

EPHA1
Ephrin type-A receptor 1

1

5

High-throughput

0.536

High

229626

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

11

High-throughput

0.536

High

229628

MK01
Mitogen-activated protein kinase 1

1

4

High-throughput

0.536

High

229631

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

1

High-throughput

0.536

High

229635

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

20

High-throughput

0.536

High

229639

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.536

High

229650

TPTE
Putative tyrosine-protein phosphatase TPTE

1

5

High-throughput

0.536

High

229675

CND2
Condensin complex subunit 2

1

1

High-throughput

0.536

High

229681

KLH40
Kelch-like protein 40

1

5

High-throughput

0.536

High

229690

T184A
Transmembrane protein 184A

1

1

High-throughput

0.536

High

229693

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

1

High-throughput

0.536

High

229708

NEK7
Serine/threonine-protein kinase Nek7

1

17

High-throughput

0.536

High

229712

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

18

High-throughput

0.536

High

229717

BIRC7
Baculoviral IAP repeat-containing protein 7

1

5

High-throughput

0.536

High

229722

KI16B
Kinesin-like protein KIF16B

1

11

High-throughput

0.536

High

229726

EYA1
Eyes absent homolog 1

1

6

High-throughput

0.536

High

229755

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.536

High

229670

IF4A2
Eukaryotic initiation factor 4A-II

1

9

High-throughput

0.515

High

175356

PPM1D
Protein phosphatase 1D

1

0

High-throughput

0.513

High

229609

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.513

High

229646

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

229676

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.513

High

229685

VASN
Vasorin

1

0

High-throughput

0.513

High

229692

CYS1
Cystin-1

1

0

High-throughput

0.513

High

229695

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

229700

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

0

High-throughput

0.513

High

229710

ACO12
Acetyl-coenzyme A thioesterase

1

0

High-throughput

0.513

High

229718

ATG4C
Cysteine protease ATG4C

1

0

High-throughput

0.513

High

229724

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.513

High

229728

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.513

High

229737

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

229654

MAX
Protein max

1

7

Small-scale

0.512

High

229731

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.508

High

229714

EXOC4
Exocyst complex component 4

1

0

Small-scale

0.493

High

229715

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.493

High

213093

SNG1
Synaptogyrin-1

1

1

High-throughput

0.489

High

229620

F163B
Protein FAM163B

1

1

High-throughput

0.489

High

229647

EFNA4
Ephrin-A4

1

5

High-throughput

0.489

High

229688

STYK1
Tyrosine-protein kinase STYK1

1

12

High-throughput

0.489

High

229689

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

229704

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.489

High

229706

SYNPR
Synaptoporin

1

1

High-throughput

0.489

High

229719

F163A
Protein FAM163A

1

1

High-throughput

0.489

High

229725

PSKH2
Serine/threonine-protein kinase H2

1

5

High-throughput

0.489

High

229735

CBX8
Chromobox protein homolog 8

1

7

High-throughput

0.489

High

229742

MED9
Mediator of RNA polymerase II transcription subunit 9

1

1

High-throughput

0.489

High

229754

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

3

High-throughput

0.489

High

229757

T184B
Transmembrane protein 184B

1

1

High-throughput

0.489

High

229738

PNRC2
Proline-rich nuclear receptor coactivator 2

1

0

High-throughput

0.486

High

225985

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

229613

ABL1
Tyrosine-protein kinase ABL1

1

7

Small-scale

0.479

High

229614

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

229616

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

229621

BCR
Breakpoint cluster region protein

1

13

High-throughput

0.479

High

229622

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

229629

PML
Protein PML

1

8

High-throughput

0.479

High

229630

WEE1
Wee1-like protein kinase

1

18

High-throughput

0.479

High

229634

MCM7
DNA replication licensing factor MCM7

1

14

High-throughput

0.479

High

229636

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

229637

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

229638

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

229640

MK08
Mitogen-activated protein kinase 8

1

20

Small-scale

0.479

High

229641

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

20

Small-scale

0.479

High

229642

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

20

Small-scale

0.479

High

229643

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

229644

MCM2
DNA replication licensing factor MCM2

1

15

High-throughput

0.479

High

229645

RAB9A
Ras-related protein Rab-9A

1

9

High-throughput

0.479

High

229649

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

229652

RAB10
Ras-related protein Rab-10

1

10

Small-scale

0.479

High

229653

UBC12
NEDD8-conjugating enzyme Ubc12

1

3

High-throughput

0.479

High

229656

H31
Histone H3.1

1

7

High-throughput

0.479

High

229658

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

229660

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

229661

KIF23
Kinesin-like protein KIF23

1

15

High-throughput

0.479

High

229662

SOX4
Transcription factor SOX-4

1

3

High-throughput

0.479

High

229663

EP300
Histone acetyltransferase p300

1

13

High-throughput

0.479

High

229666

ANK3
Ankyrin-3

1

8

High-throughput

0.479

High

229667

TP4A2
Protein tyrosine phosphatase type IVA 2

1

5

High-throughput

0.479

High

229668

CUL4A
Cullin-4A

1

10

High-throughput

0.479

High

229672

SMC1A
Structural maintenance of chromosomes protein 1A

1

18

High-throughput

0.479

High

229674

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

9

High-throughput

0.479

High

229677

MK14
Mitogen-activated protein kinase 14

1

20

Small-scale

0.479

High

229684

RN123
E3 ubiquitin-protein ligase RNF123

1

13

High-throughput

0.479

High

229686

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

229691

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

229696

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

229711

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

229713

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.479

High

229727

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

10

Small-scale

0.479

High

229730

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.479

High

229732

WWTR1
WW domain-containing transcription regulator protein 1

1

13

High-throughput

0.479

High

229733

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.479

High

229734

ECT2
Protein ECT2

1

14

High-throughput

0.479

High

229740

ANLN
Anillin

1

6

High-throughput

0.479

High

229741

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

229744

PD1L1
Programmed cell death 1 ligand 1

1

5

Small-scale

0.479

High

229746

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

1

High-throughput

0.479

High

229748

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

229752

CD11A
Cyclin-dependent kinase 11A

1

14

High-throughput

0.479

High

229753

SMC3
Structural maintenance of chromosomes protein 3

1

10

High-throughput

0.479

High

229756

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

10

High-throughput

0.479

High

229758

NS1BP
Influenza virus NS1A-binding protein

1

4

High-throughput

0.479

High

229678

ZN239
Zinc finger protein 239

1

1

Small-scale

0.462

High

229687

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.458

High

229705

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

229743

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

High-throughput

0.458

High

229610

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

229615

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.437

High

229633

MCM4
DNA replication licensing factor MCM4

1

14

High-throughput

0.437

High

229671

MCM6
DNA replication licensing factor MCM6

1

15

High-throughput

0.437

High

229694

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

229699

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

229709

TF3C2
General transcription factor 3C polypeptide 2

1

1

High-throughput

0.437

High

229716

ATG2B
Autophagy-related protein 2 homolog B

1

1

High-throughput

0.437

High

229736

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

2

High-throughput

0.437

High

229739

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

229750

TF3C4
General transcription factor 3C polypeptide 4

1

1

High-throughput

0.437

High

229680

ATG2A
Autophagy-related protein 2 homolog A

1

1

Small-scale

0.407

High

229683

F219B
Protein FAM219B

3

0

High-throughput

0.347

High

229679

TMM44
Transmembrane protein 44

2

0

High-throughput

0.328

High

229697

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

0

High-throughput

0.328

High

229707

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

229729

MND1
Meiotic nuclear division protein 1 homolog

2

0

High-throughput

0.328

High

229747

CCG5
Voltage-dependent calcium channel gamma-5 subunit

2

0

High-throughput

0.328

High

210516

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.279

Low

229608

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

229659

CD83
CD83 antigen

1

0

High-throughput

0.279

Low

229682

GSAML
Germinal center-associated signaling and motility-like protein

1

0

High-throughput

0.279

Low

229698

CA210
Type III endosome membrane protein TEMP

1

0

High-throughput

0.279

Low

229720

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

0

High-throughput

0.279

Low

229749

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

59383

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.249

Low

229745

RELCH
RAB11-binding protein RELCH

1

0

High-throughput

0.249

Low

229627

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024