HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2229 Hs			1 1191
+	Hs
		1127618 PRC2B_HUMAN (1-2229): 0: 619: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1335262 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1136360 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136381 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		257620 PRC2B_HUMAN (1-2229): 0: 619: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		1127685 PRC2B_HUMAN (1-2229): 0: 619: 100.00		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82
+	Hs
		325944 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		311825 TACC2_HUMAN (220-2228): 4.35e-33: 143: 9.07		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		257726 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		554259 MUC1_HUMAN (92-987): 9.05e-19: 96: 9.37		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		325829 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Mm
		1351630 PCLO_MOUSE (15-1858): 1.65e-14: 82.4: 8.18		PCLO_MOUSE (522-1015): 6.21e-15: 82.8: 8.09
+	Mm
		612540 EIF3A_MOUSE (842-1525): 6.47e-14: 80.2: 11.41		IF4G1_MOUSE (575-1137): 6.45e-15: 82.4: 11.00
+	Hs
		1300971 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		CHD7_HUMAN (491-1004): 4.82e-13: 76.2: 7.21
+	Hs
		1056876 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		MICA3_HUMAN (347-1112): 2.37e-13: 77.4: 8.93
+	Hs
		1056827 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Dm
		113976 M9PB30_DROME (1183-1955): 1.05e-13: 79.8: 9.22		M9PB30_DROME (683-1171): 5.39e-11: 69.7: 12.25
+	Hs
		1270850 NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		867119 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		SC24C_HUMAN (362-642): 1.58e-09: 64.6: 12.98
+	Hs
		1056910 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77