Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: RIT1 (Q92963)
GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)
Gene: RIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 29513927
Identification Methods pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Roc
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2527
Hs

1 219
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024