HitPredict

Interactor 1: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Interactor 2: I2BP2 (Q7Z5L9)
Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)
Gene: IRF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 502 Hs			1 587
+	Hs
		1133513 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		I2BP1_HUMAN (5-586): 1.23e-67: 231: 30.21
+	Hs
		1087832 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		I2BP2_HUMAN (1-587): 1.49e-95: 305: 100.00
+	Hs
		474093 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		I2BP2_HUMAN (1-587): 1.49e-95: 305: 100.00
+	Hs
		143082 NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69		I2BP2_HUMAN (1-587): 1.49e-95: 305: 100.00
+	Hs
		1087852 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		I2BP1_HUMAN (5-586): 1.23e-67: 231: 30.21
+	Hs
		474109 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		I2BP1_HUMAN (5-586): 1.23e-67: 231: 30.21
+	Hs
		1133653 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		I2BPL_HUMAN (4-280): 1.7e-18: 91.7: 25.63
+	Hs
		143101 NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69		I2BP1_HUMAN (5-586): 1.23e-67: 231: 30.21
+	Hs
		1133540 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		KMT2C_HUMAN (59-497): 3.38e-12: 72.1: 9.85
+	Hs
		1133766 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		CABIN_HUMAN (92-338): 4.42e-09: 61.6: 14.34
+	Hs
		1088007 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		I2BPL_HUMAN (4-280): 1.7e-18: 91.7: 25.63
+	Hs
		474279 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		I2BPL_HUMAN (4-280): 1.7e-18: 91.7: 25.63
+	Hs
		1087875 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		KMT2C_HUMAN (59-497): 3.38e-12: 72.1: 9.85
+	Hs
		1088135 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		CABIN_HUMAN (92-338): 4.42e-09: 61.6: 14.34
+	Hs
		474133 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		KMT2C_HUMAN (59-497): 3.38e-12: 72.1: 9.85
+	Hs
		474412 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		CABIN_HUMAN (92-338): 4.42e-09: 61.6: 14.34
+	Hs
		143246 NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69		I2BPL_HUMAN (4-280): 1.7e-18: 91.7: 25.63
+	Hs
		143124 NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69		KMT2C_HUMAN (59-497): 3.38e-12: 72.1: 9.85
+	Hs
		143359 NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69		CABIN_HUMAN (92-338): 4.42e-09: 61.6: 14.34
+	Mm
		1455913 PCLO_MOUSE (215-500): 2.99e-12: 71.6: 13.54		PCLO_MOUSE (83-508): 2.3e-12: 72.4: 7.19