Interactor 1: INT11 (Q5TA45)
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)
Gene: INTS11

Interactor 2: INT9 (Q9NV88)
Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74)
Gene: INTS9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 24981860, 33961781, 16239144, 28396433, 33548203
Identification Methods affinity chromatography technology, x-ray crystallography, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, pull down, cross-linking study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-Casp~Beta-Casp, Beta-Casp~Lactamase_B_6, Lactamase_B_6~Lactamase_B_6, Beta-Casp~RMMBL, Lactamase_B_6~RMMBL
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016180 - snRNA processing
GO:0032039 - integrator complex
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 600
Hs

1 658
+ Dm
+ At
+ Zm
+ At
+ At
+ Sp
+ Hs
+ Dm
+ At
+ At
+ Sp
+ Sc
+ At
+ Mt

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Last updated: 15 Jul 2024