HitPredict

Interactor 1: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Interactor 2: LUR1L (Q8IV03)
Leucine rich adaptor protein 1-like
Gene: LURAP1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1732 Hs			1 228
+	Hs
		1137896 MRCKA_HUMAN (1-1732): 0: 1615: 100.00		LURA1_HUMAN (3-196): 2.43e-72: 221: 36.55
+	Rn
		88957 MRCKA_RAT (1-1732): 0: 1611: 95.90		LURA1_RAT (3-197): 1.3e-73: 225: 37.81
+	Hs
		1217032 MRCKB_HUMAN (1-1731): 0: 1417: 60.38		LUR1L_HUMAN (1-228): 1.55e-92: 272: 100.00
+	Rn
		88958 MRCKB_RAT (1-1731): 0: 1422: 60.14		LURA1_RAT (3-197): 1.3e-73: 225: 37.81
+	Hs
		1297344 MRCKB_HUMAN (1-1731): 0: 1417: 60.38		LURA1_HUMAN (3-196): 2.43e-72: 221: 36.55
+	Hs
		1150621 MRCKG_HUMAN (4-1712): 0: 1145: 39.90		LUR1L_HUMAN (1-228): 1.55e-92: 272: 100.00
+	Hs
		1150630 MRCKG_HUMAN (4-1712): 0: 1145: 39.90		LURA1_HUMAN (3-196): 2.43e-72: 221: 36.55
+	Hs
		254507 ROCK2_HUMAN (373-1052): 1.4e-22: 108: 12.07		LURA1_HUMAN (3-196): 2.43e-72: 221: 36.55