HitPredict

Interactor 1: SYDE2 (Q5VT97)
Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2)
Gene: SYDE2

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32203420, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Hs			1 817
+	Mm
		1160684 BCR_MOUSE (533-1038): 2.5e-74: 272: 24.04		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		876498 RHG39_HUMAN (312-1033): 5.64e-109: 369: 14.00		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		1021850 ABR_HUMAN (519-1038): 2.32e-85: 298: 22.06		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Mm
		886881 RHG39_MOUSE (270-1033): 5.22e-99: 342: 12.58		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		876410 RHG21_HUMAN (373-1189): 9.41e-95: 336: 17.25		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Mm
		250653 SRGP1_MOUSE (397-1177): 2.27e-92: 322: 14.10		LNX1_MOUSE (273-773): 1.71e-32: 137: 12.03
+	Hs
		876424 SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		1021847 ABR_HUMAN (519-1038): 2.32e-85: 298: 22.06		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		1271026 RGAP1_HUMAN (529-1118): 3.07e-75: 264: 16.67		DLG3_HUMAN (154-707): 4.39e-44: 173: 12.27
+	Hs
		506646 BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Mm
		250652 SRGP2_MOUSE (397-1194): 6.45e-83: 295: 13.95		LNX1_MOUSE (273-773): 1.71e-32: 137: 12.03
+	Mm
		1131438 ABR_MOUSE (519-1038): 1.9e-85: 298: 22.24		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		253330 SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Mm
		250626 BCR_MOUSE (533-1038): 2.5e-74: 272: 24.04		LNX1_MOUSE (273-773): 1.71e-32: 137: 12.03
+	Hs
		506626 BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Hs
		1173142 SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Hs
		506555 BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		253346 SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95		PTN13_HUMAN (204-781): 3.8e-18: 92.3: 9.74
+	Hs
		253399 SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Hs
		506645 BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48